Phosphodiesterase type 5 inhibition improves early memory consolidation of object information.
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Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian speciesSynthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's diseasePhosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and CognitionPDE5 inhibition improves object memory in standard housed rats but not in rats housed in an enriched environment: implications for memory models?Phosphodiesterases as therapeutic targets for Alzheimer's disease.Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J miceUsing the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia.Repeated antidepressant therapy increases cyclic GMP signaling in rat hippocampusNeuroprotective effects of tadalafil on gerbil dopaminergic neurons following cerebral ischemiaPleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage.Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatmentPDE5 inhibitors beyond erectile dysfunction.Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.A placebo-controlled study of sildenafil effects on cognition in schizophrenia.Role of phosphodiesterase 5 in synaptic plasticity and memorycGMP-dependent protein kinase I, the circadian clock, sleep and learning.Clinical and molecular genetics of the phosphodiesterases (PDEs).Modulating nitric oxide signaling in the CNS for Alzheimer's disease therapy.Effects of zaprinast and rolipram on olfactory and visual memory in the social transmission of food preference and novel object recognition tests in mice.Extracellular cGMP Modulates Learning Biphasically by Modulating Glycine Receptors, CaMKII and Glutamate-Nitric Oxide-cGMP Pathway.Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives.Zaprinast and rolipram enhances spatial and emotional memory in the elevated plus maze and passive avoidance tests and diminishes exploratory activity in naive miceUse of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis.Selective inhibition of phosphodiesterase 5 enhances glutamatergic synaptic plasticity and memory in mice.Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling.The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans.Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats.Role of PDE9 in Cognition.Phosphodiesterase type 5 and cancers: progress and challenges.From Age-Related Cognitive Decline to Alzheimer's Disease: A Translational Overview of the Potential Role for Phosphodiesterases.Sildenafil Improves Vascular and Metabolic Function in Patients with Alzheimer's Disease.Cilostazol improves hippocampus-dependent long-term memory in mice.Genetic Understanding of Stroke Treatment: Potential Role for Phosphodiesterase Inhibitors.Use of behavioural and long-term potentiation models in the development of memory-improving drugs.A novel synthetic phosphodiesterase 5 inhibitor, KJH-1002, ameliorates scopolamine-induced cognitive impairments in mice by activating the cGMP/CREB signaling pathway and attenuating oxidative damage.The effects of the soluble guanylate cyclase stimulator riociguat on memory performance in healthy volunteers with a biperiden-induced memory impairment
P2860
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P2860
Phosphodiesterase type 5 inhibition improves early memory consolidation of object information.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Phosphodiesterase type 5 inhib ...... idation of object information.
@ast
Phosphodiesterase type 5 inhib ...... idation of object information.
@en
type
label
Phosphodiesterase type 5 inhib ...... idation of object information.
@ast
Phosphodiesterase type 5 inhib ...... idation of object information.
@en
prefLabel
Phosphodiesterase type 5 inhib ...... idation of object information.
@ast
Phosphodiesterase type 5 inhib ...... idation of object information.
@en
P2093
P1476
Phosphodiesterase type 5 inhib ...... idation of object information.
@en
P2093
Arjan Blokland
Franz Josef van der Staay
Guido Koopmans
Jan de Vente
Jos Prickaerts
Wilma C G van Staveren
P304
P356
10.1016/J.NEUINT.2004.03.022
P577
2004-11-01T00:00:00Z