Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions - Wikidata - awgldk - TriplyDB

Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions

Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions

http://www.wikidata.org/entity/Q35870471

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Gene-based therapy of Parkinson's Disease: Translation from animal model to human clinical trial employing convection enhanced delivery Rapid inverse planning for pressure-driven drug infusions in the brain Automated segmentation tool for brain infusions MRI-based computational model of heterogeneous tracer transport following local infusion into a mouse hind limb tumor Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study Image-guided convection-enhanced delivery platform in the treatment of neurological diseases.Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors Anatomical differences determine distribution of adenovirus after convection-enhanced delivery to the rat brain.Image-guided convection-enhanced delivery into agarose gel models of the brain Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1.Magnetic resonance imaging properties of convective delivery in diffuse intrinsic pontine gliomas.Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans.Convection-enhanced drug delivery of interleukin-4 Pseudomonas exotoxin (PRX321): increased distribution and magnetic resonance monitoring.Predictive models for pressure-driven fluid infusions into brain parenchyma.Immunotherapy of malignant brain tumors.Jeannette Wilkins Award: Can locally delivered gadolinium be visualized on MRI? A pilot study.Evaluation of pressure-driven brain infusions in nonhuman primates by intra-operative 7 Tesla MRI.Spatiotemporal quantification of local drug delivery using MRI.Convection-enhanced delivery for the treatment of brain tumors.Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.Voxelized computational model for convection-enhanced delivery in the rat ventral hippocampus: comparison with in vivo MR experimental studies.Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery.Non-PEGylated liposomes for convection-enhanced delivery of topotecan and gadodiamide in malignant glioma: initial experience.Voxelized Model of Brain Infusion That Accounts for Small Feature Fissures: Comparison With Magnetic Resonance Tracer Studies Convection-enhanced delivery in the treatment of epilepsy.Targeted drug delivery for treatment and imaging of glioblastoma multiforme.Future of convection-enhanced delivery in the treatment of brain tumors.Molecular neurosurgery: vectors and vector delivery strategies.Diphtheria toxin-based targeted toxin therapy for brain tumors.Convection-enhanced delivery for glioblastoma: targeted delivery of antitumor therapeutics.Convection-Enhanced Delivery.Convection-Enhanced Delivery for Diffuse Intrinsic Pontine Glioma Treatment.Current status of intratumoral therapy for glioblastoma.Interstitial chemotherapy for malignant glioma: Future prospects in the era of multimodal therapy A novel ligand delivery system to non-invasively visualize and therapeutically exploit the IL13Rα2 tumor-restricted biomarker.Delivering therapy to target: improving the odds for successful drug development.Analysis of a simulation algorithm for direct brain drug delivery.Convection-enhanced drug delivery for gliomas.

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P2860

Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions

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David Croteau

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Ira Pastan

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James E Herndon

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James M Provenzale

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John H Sampson

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Martin L Brady

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María Inmaculada Rodríguez-Ponce

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Philipp Tanner

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R Edward Coleman

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P2860

Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin.

Transport of molecules across tumor vasculature.

The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery.

Convection-enhanced delivery of macromolecules in the brain.

Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study

AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters.

Tumor physiology and antibody delivery.

Vascular and interstitial barriers to delivery of therapeutic agents in tumors.

Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors.

Transport of molecules in the tumor interstitium: a review.

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