Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment. - Wikidata - awgldk - TriplyDB

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.

http://www.wikidata.org/entity/Q35876209

about

Newer gene editing technologies toward HIV gene therapy Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives Bone Marrow Gene Therapy for HIV/AIDS Studies of retroviral infection in humanized mice T-cell therapies for HIV Expanding the scope of site-specific recombinases for genetic and metabolic engineering Recent developments in human immunodeficiency virus-1 latency research New generation humanized mice for virus research: comparative aspects and future prospects Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice Targeted gene disruption to cure HIV Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates.Engineering T Cells to Functionally Cure HIV-1 Infection Prospects for treatment of latent HIV.Genome-Edited T Cell Therapies.Combinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAART Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering Genome editing strategies: potential tools for eradicating HIV-1/AIDS.RNA interference approaches for treatment of HIV-1 infection Combined Antiviral Therapy Using Designed Molecular Scaffolds Targeting Two Distinct Viral Functions, HIV-1 Genome Integration and Capsid Assembly Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection.The clinical applications of genome editing in HIV.Altering cell death pathways as an approach to cure HIV infection.Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance.Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection.A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells.Glycosylphosphatidylinositol-Anchored Anti-HIV scFv Efficiently Protects CD4 T Cells from HIV-1 Infection and Deletion in hu-PBL Mice.Advances in targeted genome editing.Creating genetic resistance to HIV.HIV/AIDS: modified stem cells in the spotlight.Potential mechanisms for cell-based gene therapy to treat HIV/AIDS.Cell therapies for treatment of human immunodeficiency virus infection.Personalized gene therapy locks out HIV, paving the way to control virus without antiretroviral drugs.Cell-based gene therapy against HIV.Developmental history and application of CRISPR in human disease.Stem cell-based therapies for HIV/AIDS.T-cell therapies for HIV: Preclinical successes and current clinical strategies.Enhanced gene disruption by programmable nucleases delivered by a minicircle vector.Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials.Novel AIDS therapies based on gene editing.Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors.

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P2860

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.

http://www.wikidata.org/entity/Q35876209

description

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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Molecular Therapy

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Zinc-finger nuclease editing o ...... ell resistance and enrichment.

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P2093

Bruce E Torbett

http://www.w3.org/2001/XMLSchema#string

Colleen Fearns

http://www.w3.org/2001/XMLSchema#string

Jianbin Wang

http://www.w3.org/2001/XMLSchema#string

Jinyun Yuan

http://www.w3.org/2001/XMLSchema#string

Karen Crain

http://www.w3.org/2001/XMLSchema#string

Kenneth A Kim

http://www.w3.org/2001/XMLSchema#string

Kevin L Hua

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Michael C Holmes

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Philip D Gregory

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P2860

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Identification of a major co-receptor for primary isolates of HIV-1

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector

CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection

Enhancing gene targeting with designed zinc finger nucleases

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Genome editing with engineered zinc finger nucleases

An improved zinc-finger nuclease architecture for highly specific genome editing

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10.1038/MT.2011.310

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20

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22273578

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3321595

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