Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A
about
Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone FunctionalityInsight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human InsulinStructural and functional study of the GlnB22-insulin mutant responsible for maturity-onset diabetes of the youngInsulin and insulin like growth factor II endocytosis and signaling via insulin receptor BClass III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling.Decorin differentially modulates the activity of insulin receptor isoform A ligands.Reciprocal regulation of endocytosis and metabolismSomething old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationLigand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function.Sortilin regulates progranulin action in castration-resistant prostate cancer cellsLigand-Binding Affinity at the Insulin Receptor Isoform-A and Subsequent IR-A Tyrosine Phosphorylation Kinetics are Important Determinants of Mitogenic Biological Outcomes.Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses.Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagyHuman IGF1 extends lifespan and enhances resistance to Plasmodium falciparum infection in the malaria vector Anopheles stephensiDichotomy of decorin activity on the insulin-like growth factor-I systemFratricide of natural killer cells dressed with tumor-derived NKG2D ligand.Ephrin-B2 controls PDGFRβ internalization and signaling.Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansionCD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling.Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus.Pre-B cell colony enhancing factor induces Nampt-dependent translocation of the insulin receptor out of lipid microdomains in A549 lung epithelial cells.The neuronal insulin receptor in its environment.Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells.Rational steering of insulin binding specificity by intra-chain chemical crosslinkingIGF-I, IGF-II, and Insulin Stimulate Different Gene Expression Responses through Binding to the IGF-I Receptor.Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.Insulin receptor membrane retention by a traceable chimeric mutant.The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications.Insulin Receptor Isoforms in Physiology and Disease: An Updated View.IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling.[Involvement of the endosomal compartment in cellular insulin signaling].A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding
P2860
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P2860
Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Insulin and insulin-like growt ...... of insulin receptor isoform A
@ast
Insulin and insulin-like growt ...... of insulin receptor isoform A
@en
type
label
Insulin and insulin-like growt ...... of insulin receptor isoform A
@ast
Insulin and insulin-like growt ...... of insulin receptor isoform A
@en
prefLabel
Insulin and insulin-like growt ...... of insulin receptor isoform A
@ast
Insulin and insulin-like growt ...... of insulin receptor isoform A
@en
P2093
P2860
P50
P356
P1476
Insulin and insulin-like growt ...... of insulin receptor isoform A
@en
P2093
Alaide Morcavallo
Andrea Morrione
Andrzej M Brzozowski
Angela Palummo
Emilia Kletvikova
P2860
P304
11422-11436
P356
10.1074/JBC.M111.252478
P407
P577
2012-02-08T00:00:00Z