ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
about
Metastatic canine mammary carcinomas can be identified by a gene expression profile that partly overlaps with human breast cancer profilesInteractions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathwaysRetroviral oncogenes: a historical primerThe NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor geneOverexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involutionNuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells.The role of EGFR family inhibitors in muscle invasive bladder cancer: a review of clinical data and molecular evidenceThe localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer.Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.E3 ubiquitin ligases in ErbB receptor quantity control.The prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients.Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling.Estrogen-induced upregulation of Sftpb requires transcriptional control of neuregulin receptor ErbB4 in mouse lung type II epithelial cells.Frequent gene amplification predicts poor prognosis in gastric cancer.Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor familyAn essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancerNeuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptakeErbB3 downregulation enhances luminal breast tumor response to antiestrogens.ErbB4 is an upstream regulator of TTF-1 fetal mouse lung type II cell development in vitro.Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model.Presence of HER4 associates with increased sensitivity to Herceptin in patients with metastatic breast cancer.Role of the Neuregulin Signaling Pathway in Nicotine Dependence and Co-morbid Disorders.Biomarkers and endosalpingiosis in the ovarian and tubal microenvironment of women at high-risk for pelvic serous carcinoma.Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype.Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1.Potential of ErbB4 antibodies for cancer therapy.Multiple Functional Motifs Are Required for the Tumor Suppressor Activity of a Constitutively-Active ErbB4 Mutant.Molecular regulators of pubertal mammary gland development.Neuregulin 3 and erbb signalling networks in embryonic mammary gland development.Neuregulin-ErbB4 signaling in the developing lung alveolus: a brief review.Targeting HER family in HER2-positive metastatic breast cancer: potential biomarkers and novel targeted therapies.EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.Mesenchymal stem cells exploit extracellular matrix as mechanotransducer.ErbB1-4-dependent EGF/neuregulin signals and their cross talk in the central nervous system: pathological implications in schizophrenia and Parkinson's disease.The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN+ oral squamous cell carcinoma with extranodal spread.
P2860
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P2860
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@ast
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@en
type
label
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@ast
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@en
prefLabel
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@ast
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@en
P2093
P2860
P1476
ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition.
@en
P2093
H Shelton Earp
Karen E Strunk
Rebecca S Muraoka-Cook
Shu-Mang Feng
P2860
P2888
P304
P356
10.1007/S10911-008-9080-X
P577
2008-04-25T00:00:00Z