Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
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Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitorNrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 miceAlleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitisAnti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cellsEstablishment of the tree shrew as an alcohol-induced Fatty liver model for the study of alcoholic liver diseasesMultilayered epithelium in a rat model and human Barrett's esophagus: similar expression patterns of transcription factors and differentiation markers.Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cellsRevolving door action of breast cancer resistance protein (BCRP) facilitates or controls the efflux of flavone glucuronides from UGT1A9-overexpressing HeLa cells.Enterohepatic recirculation of bioactive ginger phytochemicals is associated with enhanced tumor growth-inhibitory activity of ginger extract.UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor.UGT genomic diversity: beyond gene duplication.Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry.Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions.Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics.Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Comprehensive variant screening of the UGT gene familyStructure-activity relationships of the glucuronidation of flavonoids by human glucuronosyltransferases.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.Molecular mechanisms of Barrett's esophagus.Extrahepatic metabolism at the body's internal-external interfaces.Transcriptional regulation of human UDP-glucuronosyltransferase genes.Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases.Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathwayPradigastat disposition in humans: in vivo and in vitro investigations.Expression of UDP-glucuronosyltransferase 1A in bladder cancer: association with prognosis and regulation by estrogen.Androgen receptor signals regulate UDP-glucuronosyltransferases in the urinary bladder: a potential mechanism of androgen-induced bladder carcinogenesis.Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.Compendium of gene expression profiles comprising a baseline model of the human liver drug metabolism transcriptome.Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry.Species- and gender-dependent differences in the glucuronidation of a flavonoid glucoside and its aglycone determined using expressed UGT enzymes and microsomes.Constitutive expression and phenobarbital modulation of drug metabolizing enzymes and related nuclear receptors in cattle liver and extra-hepatic tissues.The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.Effect of edible oils on quercetin, kaempferol and galangin transport and conjugation in the intestinal Caco-2/HT29-MTX co-culture modelExtrahepatic Drug-Metabolizing Enzymes and Their SignificanceCeliac disease biomarkers identified by transcriptome analysis of small intestinal biopsies
P2860
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P2860
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@ast
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@en
type
label
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@ast
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@en
prefLabel
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@ast
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract.
@en
P1476
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract
@en
P2093
Dione A Gardner-Stephen
Rikke H Lewinsky
P304
P356
10.1016/J.TAAP.2004.01.008
P577
2004-09-01T00:00:00Z