Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
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Role of PD-1 in HIV pathogenesis and as target for therapyEffector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune ResponseTargeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityThe anticancer immune response of anti-PD-1/PD-L1 and the genetic determinants of response to anti-PD-1/PD-L1 antibodies in cancer patientsMolecular and cellular insights into T cell exhaustionSignature Channels of Excitability no More: L-Type Channels in Immune CellsViewing transplantation immunology through today's lens: new models, new imaging, and new insights.Overcoming T cell exhaustion in infection and cancerNew immunotherapies targeting the PD-1 pathwayProfiling immunity to HIV vaccines with systems biologyThe enduring tale of T cells in HIV immunopathogenesisCharacterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profilingMemory T cells in transplantation - progress and challenges.Innate and Adaptive Immune Regulation During Chronic Viral InfectionsBlockade of the B7-H1/PD-1 pathway for cancer immunotherapyBET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy modelsLongitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses.CD40 signaling to the rescue: A CD8 exhaustion perspective in chronic infectious diseasesDifferential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations.T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infectionThe CD300 molecules: an emerging family of regulators of the immune system.Transcriptional control of effector and memory CD8+ T cell differentiation.Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.Loss and dysfunction of Vδ2⁺ γδ T cells are associated with clinical tolerance to malaria.IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic optionsDistinctive features of CD4+ T cell dysfunction in chronic viral infections.Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.The T-cell response to HIV.Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation.Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patientsMemories in the snow: immune memory, persistent infection and chronic diseaseCoherent functional modules improve transcription factor target identification, cooperativity prediction, and disease associationBlockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.Responsiveness of HIV-specific CD4 T cells to PD-1 blockadeBasic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expressionVaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infectionCharacterization of an effective CTL response against HIV and SIV infections.T cell exhaustion during persistent viral infections.
P2860
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P2860
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Transcriptional analysis of HI ...... function by upregulating BATF
@ast
Transcriptional analysis of HI ...... function by upregulating BATF
@en
type
label
Transcriptional analysis of HI ...... function by upregulating BATF
@ast
Transcriptional analysis of HI ...... function by upregulating BATF
@en
prefLabel
Transcriptional analysis of HI ...... function by upregulating BATF
@ast
Transcriptional analysis of HI ...... function by upregulating BATF
@en
P2093
P2860
P50
P356
P1433
P1476
Transcriptional analysis of HI ...... function by upregulating BATF
@en
P2093
Alison Crawford
Benjamin Ebert
Björn Nilsson
Boris Julg
Catia Fonseca
Daniel E Kaufmann
Douglas Dolfi
Douglas S Kwon
E John Wherry
Filippos Porichis
P2860
P2888
P304
P356
10.1038/NM.2232
P407
P577
2010-10-03T00:00:00Z