Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).
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Use of glucagon-like peptide-1 agonists to improve islet graft performancemTOR inhibitors in cancer therapyThe Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and AgingDetection of rapalog-mediated therapeutic response in renal cancer xenografts using ⁶⁴Cu-bevacizumab immunoPETStimulation of autophagy improves endoplasmic reticulum stress-induced diabetesGABAergic system in the endocrine pancreas: a new target for diabetes treatment.GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growthThe cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.Moderate calorie restriction to achieve normal weight reverses β-cell dysfunction in diet-induced obese mice: involvement of autophagyBeneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury.Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids.Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity.Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms.Protein phosphatases in pancreatic islets.Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.Inhibiting 4EBP1 in glioblastoma.Signaling crosstalk between the mTOR complexes.The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding.mTOR inhibitors in pancreas transplant: adverse effects and drug-drug interactions.Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells.Human antibody-based chemically induced dimerizers for cell therapeutic applications.Cardioprotective effects of dietary rapamycin on adult female C57BLKS/J-Leprdb mice.Everolimus Directly Suppresses Insulin Secretion Independently of Cell Growth Inhibition.
P2860
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P2860
Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@ast
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@en
type
label
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@ast
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@en
prefLabel
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@ast
Rapamycin toxicity in MIN6 cel ...... on of mTOR complex 2 (mTORC2).
@en
P2093
P2860
P1433
P1476
Rapamycin toxicity in MIN6 cel ...... ion of mTOR complex 2 (mTORC2)
@en
P2093
A D Barlow
J A M Shaw
M L Nicholson
S C Campbell
P2860
P2888
P304
P356
10.1007/S00125-012-2475-7
P577
2012-05-01T00:00:00Z