EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function
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Molecular and Cellular Effects of Hydrogen Peroxide on Human Lung Cancer Cells: Potential Therapeutic ImplicationsThe regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Regulation of Bim in Health and DiseaseCo-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.ETS-targeted therapy: can it substitute for MEK inhibitors?A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon CancerDrug Resistance to EGFR Inhibitors in Lung CancerPolo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations.HDAC10 promotes lung cancer proliferation via AKT phosphorylation.Establishment and characterization of an oral tongue squamous cell carcinoma cell line from a never-smoking patient.MAP kinase-interacting serine/threonine kinase 2 promotes proliferation, metastasis, and predicts poor prognosis in non-small cell lung cancer.ETS1 inactivation causes innate drug resistance to EGFR inhibitors.Resistance to EGFR-targeted therapy by Ets-1 inactivation.Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer.Organotypic three-dimensional cancer cell cultures mirror drug responses in vivo: lessons learned from the inhibition of EGFR signaling.Global view of a drug-sensitivity gene network.Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells.PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer.RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation.Src kinase inhibitor PP2 regulates the biological characteristics of A549 cells via the PI3K/Akt signaling pathway
P2860
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P2860
EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@ast
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@en
type
label
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@ast
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@en
prefLabel
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@ast
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@en
P2093
P2860
P356
P1476
EGFR inhibition evokes innate ...... us inactivating Ets-1 function
@en
P2093
David W Eisele
Frank McCormick
Janyaporn Phuchareon
P2860
P304
P356
10.1073/PNAS.1510733112
P407
P50
P577
2015-07-06T00:00:00Z