Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization
about
Bioengineering of noncoding RNAs for research agents and therapeuticsCo-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse modelsCombination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth.MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyGenetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest.Bioengineered non-coding RNA agent (BERA) in action.Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice.Pseudouridine in the Anticodon of Escherichia coli tRNATyr(QΨA) Is Catalyzed by the Dual Specificity Enzyme RluF.Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells.Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
P2860
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P2860
Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Bioengineering Novel Chimeric ...... nd Functional Characterization
@ast
Bioengineering Novel Chimeric ...... nd Functional Characterization
@en
type
label
Bioengineering Novel Chimeric ...... nd Functional Characterization
@ast
Bioengineering Novel Chimeric ...... nd Functional Characterization
@en
prefLabel
Bioengineering Novel Chimeric ...... nd Functional Characterization
@ast
Bioengineering Novel Chimeric ...... nd Functional Characterization
@en
P2093
P2860
P356
P1476
Bioengineering Novel Chimeric ...... nd Functional Characterization
@en
P2093
Ai-Ming Yu
Hong-Jian Zhang
Jing-Xin Qiu
Joseph L Jilek
Mei-Mei Li
Patrick A Limbach
Pui Yan Ho
Qiu-Xia Chen
Ralph DeVere White
P2860
P304
P356
10.1124/JPET.115.225631
P407
P577
2015-05-28T00:00:00Z