Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia. - Wikidata - awgldk - TriplyDB

Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia.

Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia.

http://www.wikidata.org/entity/Q35902835

about

Epigenetic modifications and diabetic retinopathy Long non-coding RNAs as regulators of the endocrine system The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment Epigenetic Regulation of Islet Development and Regeneration Early-life lead exposure results in dose- and sex-specific effects on weight and epigenetic gene regulation in weanling mice Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus Early life nutrition, epigenetics and programming of later life disease Maternal High Estradiol Exposure is Associated with Elevated Thyroxine and Pax8 in Mouse Offspring.Long non-coding RNA: Functional agent for disease traits Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism Intergenerational Effects of Endocrine Disorder on Metabolism.Intergenerational effects of prenatal ethanol on glucose tolerance and insulin response.Intergenerational and parent of origin effects of maternal calorie restriction on Igf2 expression in the adult rat hippocampus.The Missing lnc(RNA) between the pancreatic β-cell and diabetes Gene-Diet Interactions in Type 2 Diabetes: The Chicken and Egg Debate Non-coding RNAs and lipid metabolism Dietary regulation of histone acetylases and deacetylases for the prevention of metabolic diseases.Epigenetics and type II diabetes mellitus: underlying mechanisms of prenatal predisposition Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.The influence of early life nutrition on epigenetic regulatory mechanisms of the immune system.Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of pregnancy: a cross-sectional study Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats.Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes.Alteration in Expression and Methylation of IGF2/H19 in Placenta and Umbilical Cord Blood Are Associated with Macrosomia Exposed to Intrauterine Hyperglycemia.Environmental Susceptibility of the Sperm Epigenome During Windows of Male Germ Cell Development.Transgenerational Glucose Intolerance of Tumor Necrosis Factor with Epigenetic Alteration in Rat Perirenal Adipose Tissue Induced by Intrauterine Hyperglycemia Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila.Paternal transgenerational glucose intolerance with epigenetic alterations in second generation offspring of GDM.Paternal programming of offspring cardiometabolic diseases in later life Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins.Regulation of metabolism by long, non-coding RNAs Altered DNA methylation in neonates born large-for-gestational-age is associated with cardiometabolic risk in children.Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia.Epigenetic signatures of gestational diabetes mellitus on cord blood methylation.Transgenerational developmental programming.Maternal diabetes mellitus and the origin of non-communicable diseases in offspring: the role of epigenetics.DNA methylation: the pivotal interaction between early-life nutrition and glucose metabolism in later life.Environmental challenge, epigenetic plasticity and the induction of altered phenotypes in mammals.

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P2860

Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia.

http://www.wikidata.org/entity/Q35902835

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Dan Zhang

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Fan Jin

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Fang-Fang Wang

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Guo-Lian Ding

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He-Feng Huang

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Jian-Zhong Sheng

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Jing Shu

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Ning Wang

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Peter C K Leung

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Qiong Luo

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P2860

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Epigenetic reprogramming in mammalian development

Animal models of diabetes mellitus.

Genomic imprinting in mammals.

Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.

Modifiers of epigenetic reprogramming show paternal effects in the mouse.

Epigenetic events in mammalian germ-cell development: reprogramming and beyond.

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

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1133-1142

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10.2337/DB11-1314

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22447856

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