Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
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New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in InflammationADAR1, inosine and the immune sensing system: distinguishing self from non-selfSTING: infection, inflammation and cancerConverging roles of caspases in inflammasome activation, cell death and innate immunityMitochondria in the regulation of innate and adaptive immunityMitochondrial DNA: A disposable genome?DNA sensor cGAS-mediated immune recognitionThe Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor EfficacyNucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and AutoinflammationThe intersection of cell death and inflammasome activationApoptotic cell responses in the splenic marginal zone: a paradigm for immunologic reactions to apoptotic antigens with implications for autoimmunityThe Roles of Mitochondrial Damage-Associated Molecular Patterns in DiseasesDengue virus activates cGAS through the release of mitochondrial DNARegulation of platelet lifespan by apoptosis.Megakaryocytes from CYCS mutation-associated thrombocytopenia release platelets by both proplatelet-dependent and -independent processes.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.Fight or flight: regulation of emergency hematopoiesis by pyroptosis and necroptosis.Aicardi-Goutières syndrome and the type I interferonopathies.Cell death in genome evolutionOpen questions: seeking a holistic approach for mitochondrial researchThe E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.Macrophage cell death upon intracellular bacterial infection.Mitochondrial DNA in the regulation of innate immune responsesThe Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell ProliferationNeutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.The Mitochondrial Basis of Aging.Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation MachineriesThe Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I InterferonsThe intersection of radiotherapy and immunotherapy: mechanisms and clinical implications.Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune PathwaysInterferons and the Immunogenic Effects of Cancer Therapy.Activation and regulation of DNA-driven immune responses.Cytosolic sensing of aberrant DNA: arming STING on the endoplasmic reticulum.Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.Mitochondria and the hallmarks of cancer.Regulation of hematopoietic stem cell integrity through p53 and its related factors.STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity.Activation of cGAS-dependent antiviral responses by DNA intercalating agents.Mitochondrial DNA sensing by STING signaling participates in inflammation, cancer and beyond.
P2860
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P2860
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@ast
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@en
type
label
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@ast
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@en
prefLabel
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@ast
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@en
P2093
P2860
P50
P1433
P1476
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
@en
P2093
David C S Huang
Guillaume Lessene
Rachael M Lane
P2860
P304
P356
10.1016/J.CELL.2014.11.036
P407
P50
P577
2014-12-01T00:00:00Z