Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
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Rare and low-frequency coding variants alter human adult heightGWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition lociNetwork-assisted analysis of GWAS data identifies a functionally-relevant gene module for childhood-onset asthma.A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations.Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traitsAnalysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseasesBayesian association scan reveals loci associated with human lifespan and linked biomarkers.An efficient and flexible test for rare variant effects.Protein function in precision medicine: deep understanding with machine learning.Pathway-based approach using hierarchical components of collapsed rare variants.SZDB: A Database for Schizophrenia Genetic Research.The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.Functional mapping and annotation of genetic associations with FUMA.Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression.Convergence between biological, behavioural and genetic determinants of obesity.Proper joint analysis of summary association statistics requires the adjustment of heterogeneity in SNP coverage pattern.Gene co-opening network deciphers gene functional relationships.A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics.The integrated landscape of causal genes and pathways in schizophrenia.Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.Gene-level differential analysis at transcript-level resolution.A sibling method for identifying vQTLs.Detecting phenotype-driven transitions in regulatory network structure.POLARIS: Polygenic LD-adjusted risk score approach for set-based analysis of GWAS data.Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus.Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis.Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study.Genetic interaction effects reveal lipid-metabolic and inflammatory pathways underlying common metabolic disease risks.Recursive module extraction using Louvain and PageRankLarge-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypesComparison of novel and existing methods for detecting differentially methylated regions
P2860
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P2860
Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@ast
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@en
type
label
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@ast
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@en
prefLabel
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@ast
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@en
P2860
P50
P1476
Fast and Rigorous Computation ...... m SNP-Based Summary Statistics
@en
P2093
Daniel Marbach
David Lamparter
P2860
P304
P356
10.1371/JOURNAL.PCBI.1004714
P577
2016-01-25T00:00:00Z