The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B
about
Digoxin suppresses HIV-1 replication by altering viral RNA processingThe splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian developmentSequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy.A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides.Transcriptome-wide landscape of pre-mRNA alternative splicing associated with metastatic colonizationBS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processingIdentification of small molecule inhibitors of pre-mRNA splicing.Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis.Small Molecule Modulators of Pre-mRNA Splicing in Cancer TherapyTargeting RNA splicing for disease therapy.In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide MetforminDetermination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal TransitionrMAPS: RNA map analysis and plotting server for alternative exon regulation.Splicing factor TRA2B is required for neural progenitor survival.Tra2 protein biology and mechanisms of splicing control.Suppression of Adenovirus Replication by Cardiotonic Steroids.Risk of cancer in patients with heart failure who use digoxin: a 10-year follow-up study and cell-based verification.Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons.HuR regulates alternative splicing of the TRA2β gene in human colon cancer cells under oxidative stress.Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome.Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling.Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.
P2860
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P2860
The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@ast
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@en
type
label
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@ast
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@en
prefLabel
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@ast
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@en
P2093
P2860
P356
P1433
P1476
The cardiotonic steroid digito ...... licing factors SRSF3 and TRA2B
@en
P2093
Chia-Ho Lin
Christopher B Burge
Douglas L Black
Erik S Anderson
Peter Stoilov
P2860
P304
P356
10.1261/RNA.032912.112
P407
P50
P577
2012-03-28T00:00:00Z