Microtubule dynamics in vitro are regulated by the tubulin isotype composition. - Wikidata - awgldk - TriplyDB

Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

http://www.wikidata.org/entity/Q35910782

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Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functions Multiple tubulins: evolutionary aspects and biological implications Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interface.Coordination of posttranslational modifications of bovine brain alpha-tubulin. Polyglycylation of delta2 tubulin Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells Modulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cells A ubiquitous beta-tubulin disrupts microtubule assembly and inhibits cell proliferation Abraxane, the Nanoparticle Formulation of Paclitaxel Can Induce Drug Resistance by Up-Regulation of P-gp Peptide neuroprotection through specific interaction with brain tubulin An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation.Class V β-tubulin alters dynamic instability and stimulates microtubule detachment from centrosomes.Drug resistance associated with loss of p53 involves extensive alterations in microtubule composition and dynamics.One-step purification of assembly-competent tubulin from diverse eukaryotic sources.Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics Identification of betaIII- and betaIV-tubulin isotypes in cold-adapted microtubules from Atlantic cod (Gadus morhua): antibody mapping and cDNA sequencing.The differential distribution of acetylated and detyrosinated alpha-tubulin in the microtubular cytoskeleton and primary cilia of hyaline cartilage chondrocytes.The structured core of human β tubulin confers isotype-specific polymerization properties.Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics.Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility.Methods in tubulin proteomics Mechanisms of Taxol resistance related to microtubules.Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study.Docetaxel-carboxymethylcellulose nanoparticles display enhanced anti-tumor activity in murine models of castration-resistant prostate cancer.beta-Tubulin C354 mutations that severely decrease microtubule dynamics do not prevent nuclear migration in yeast.MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.Mechanisms of action and resistance to tubulin-binding agents.Drug discovery targeting cell division proteins, microtubules and FtsZ.Concentration dependence of variability in growth rates of microtubules Rationalization of paclitaxel insensitivity of yeast β-tubulin and human βIII-tubulin isotype using principal component analysis.Vinblastine suppresses dynamics of individual microtubules in living interphase cells.The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities Mutations of a redundant alpha-tubulin gene affect Caenorhabditis elegans early embryonic cleavage via MEI-1/katanin-dependent and -independent pathways.Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation.The Caenorhabditis elegans microtubule-severing complex MEI-1/MEI-2 katanin interacts differently with two superficially redundant beta-tubulin isotypes.Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations.Class III beta-tubulin in human development and cancer.

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P2860

Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

http://www.wikidata.org/entity/Q35910782

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1994 nî lūn-bûn

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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Proceedings of the National Academy of Sciences of the United States of America

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Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

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A Banerjee

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H P Miller

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L Wilson

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R F Ludueña

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P2860

Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes

Are tubulin isotypes functionally significant

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes

Characterization of posttranslational modifications in neuron-specific class III beta-tubulin by mass spectrometry

In vitro analysis of microtubule assembly of isotypically pure tubulin dimers. Intrinsic differences in the assembly properties of alpha beta II, alpha beta III, and alpha beta IV tubulin dimers in the absence of microtubule-associated proteins.

Tubulin dynamics in cultured mammalian cells.

Phase dynamics at microtubule ends: the coexistence of microtubule length changes and treadmilling.

Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies.

Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific

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