Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
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Developmental exposure to estrogen alters differentiation and epigenetic programming in a human fetal prostate xenograft modelId4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTENChanges in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 TreatmentSystems analysis of the prostate tumor suppressor NKX3.1 supports roles in DNA repair and luminal cell differentiation.A functional variant in NKX3.1 associated with prostate cancer risk in the Selenium and Vitamin E Cancer Prevention Trial (SELECT).The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Molecular pathways and targets in prostate cancerBeyond abiraterone: new hormonal therapies for metastatic castration-resistant prostate cancer.Antioxidant treatment promotes prostate epithelial proliferation in Nkx3.1 mutant mice.PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancerNovel oncogene-induced metastatic prostate cancer cell lines define human prostate cancer progression signatures.Recent progress in mouse models for tumor suppressor genes and its implications in human cancer.Molecular pathogenesis and progression of prostate cancerRAMP1 is a direct NKX3.1 target gene up-regulated in prostate cancer that promotes tumorigenesis.Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation.Loss of the NKX3.1 tumorsuppressor promotes the TMPRSS2-ERG fusion gene expression in prostate cancer.Therapeutic Approaches Targeting MYC-Driven Prostate CancerLack of an additive effect between the deletions of Klf5 and Nkx3-1 in mouse prostatic tumorigenesis.Coregulation of genetic programs by the transcription factors NFIB and STAT5.Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression.Systematic enrichment analysis of potentially functional regions for 103 prostate cancer risk-associated loci.Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation.4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer.Alterations of C-MYC, NKX3.1, and E-cadherin expression in canine prostate carcinogenesis.PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.Immunohistochemical panel to characterize canine prostate carcinomas according to aberrant p63 expression.Recent Advances in Liquid Biopsy in Patients With Castration Resistant Prostate CancerGlutathione Peroxidase 2, a Selenoprotein Exhibiting a Dual Personality in Preventing and Promoting Cancer
P2860
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P2860
Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@ast
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@en
type
label
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@ast
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@en
prefLabel
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@ast
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@en
P2093
P2860
P356
P1476
Nkx3.1 and Myc crossregulate s ...... human prostate tumorigenesis.
@en
P2093
Christine M Eischen
Irina Doubinskaia
Isam-Eldin Eltoum
Meejeon Roh
Monica Logan
Omar E Franco
Philip D Anderson
Riet van der Meer
Sarki A Abdulkadir
P2860
P304
P356
10.1172/JCI58540
P407
P577
2012-04-09T00:00:00Z