Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
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Mutations in the transmembrane natriuretic peptide receptor NPR-B impair skeletal growth and cause acromesomelic dysplasia, type MaroteauxRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpOsteocrin is a specific ligand of the natriuretic Peptide clearance receptor that modulates bone growthThe natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide systemDwarfism and early death in mice lacking C-type natriuretic peptideThe systemic nature of CKD.BNP signaling is crucial for embryonic stem cell proliferation.The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth.Molecular, phenotypic aspects and therapeutic horizons of rare genetic bone disorders.Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regenerationEstrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association.A human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B.Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3).Cardiac fibrosis in mice lacking brain natriuretic peptideThe biology of cyclic GMP-dependent protein kinases.The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications.Musclin is an activity-stimulated myokine that enhances physical endurance.A Track Record on SHOX: From Basic Research to Complex Models and TherapyAccelerated puberty and late-onset hypothalamic hypogonadism in female transgenic skinny mice overexpressing leptin.Nitric oxide, C-type natriuretic peptide and cGMP as regulators of endochondral ossification.Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes.Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasiasNPPB and ACAN, two novel SHOX2 transcription targets implicated in skeletal development.Natriuretic peptide system: an overview of studies using genetically engineered animal models.FGFR3 targeting strategies for achondroplasia.Ularitide: a natriuretic peptide candidate for the treatment of acutely decompensated heart failure.Advances in treatment of achondroplasia and osteoarthritis.Current Care and Investigational Therapies in Achondroplasia.Achondroplasia: Development, pathogenesis, and therapy.NPR-A regulates self-renewal and pluripotency of embryonic stem cells.Chronically elevated plasma C-type natriuretic peptide level stimulates skeletal growth in transgenic mice.Cyclic GMP-dependent protein kinase regulates CCAAT enhancer-binding protein beta functions through inhibition of glycogen synthase kinase-3.Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.Localization of Brain Natriuretic Peptide Immunoreactivity in Rat Spinal Cord.Characterization of two ENU-induced mutations affecting mouse skeletal morphology.Proliferative actions of natriuretic peptides on neuroblastoma cells. Involvement of guanylyl cyclase and non-guanylyl cyclase pathways.Vasopressin-dependent inhibition of the C-type natriuretic peptide receptor, NPR-B/GC-B, requires elevated intracellular calcium concentrations.Short stature homeobox-containing gene duplications in 3.7% of girls with tall stature and normal karyotypes.Natriuretic peptide regulation of endochondral ossification. Evidence for possible roles of the C-type natriuretic peptide/guanylyl cyclase-B pathway.
P2860
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P2860
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@ast
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@en
type
label
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@ast
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@en
prefLabel
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@ast
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@en
P2093
P2860
P356
P1476
Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide
@en
P2093
H Nishimoto
T Takigawa
P2860
P304
P356
10.1073/PNAS.95.5.2337
P407
P577
1998-03-01T00:00:00Z