Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
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The ANG-(1-7)/ACE2/mas axis in the regulation of nephron functionPhysiology of kidney reninCharacterization of angiotensin-converting enzyme 2 ectodomain shedding from mouse proximal tubular cellsReduction in renal ACE2 expression in subtotal nephrectomy in rats is ameliorated with ACE inhibitionRole of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease.Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension.Potential Role of Serum and Urinary Biomarkers in Diagnosis and Prognosis of Diabetic Nephropathy.Classical Renin-Angiotensin system in kidney physiologyAttenuation of hypertension-mediated glomerulosclerosis in conjunction with increased angiotensin (1-7).Angiotensin converting enzyme (ACE) and ACE2 bind integrins and ACE2 regulates integrin signalling.Recent advances involving the renin-angiotensin systemIncreased urinary angiotensin-converting enzyme 2 in renal transplant patients with diabetes.Nonclassical renin-angiotensin system and renal function.ACE2 and diabetes: ACE of ACEs?Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibitionIdentification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injuryAngiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.Loss of ACE2 exacerbates murine renal ischemia-reperfusion injury.Short-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy.Angiotensin-converting enzyme 2: the first decade.Angiotensin converting enzyme 2, Angiotensin-(1-7), and receptor MAS axis in the kidney.Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative StressDifferential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes.Diabetic Nephropathy Induced by Increased Ace Gene Dosage Is Associated with High Renal Levels of Angiotensin (1-7) and BradykininRole of upstream stimulatory factor 2 in diabetic nephropathy.Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice.Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway.Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet.ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis.Angiotensin-converting enzyme 2 and the kidney.Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart FailureHigh glucose-induced Nox1-derived superoxides downregulate PKC-betaII, which subsequently decreases ACE2 expression and ANG(1-7) formation in rat VSMCsAngiotensin converting enzyme 2 in the kidney.Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axisAngiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages.The sweeter side of ACE2: physiological evidence for a role in diabetes.Loss of TIMP3 enhances interstitial nephritis and fibrosis.
P2860
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P2860
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@ast
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@en
type
label
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@ast
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@en
prefLabel
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@ast
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@en
P2093
P2860
P1476
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
@en
P2093
Andrew M Herzenberg
Denise W Wong
Gavin Y Oudit
Heather Reich
James W Scholey
Joyce Zhou
Peter H Backx
Qiao C Liu
Zamaneh Kassiri
P2860
P304
P356
10.2353/AJPATH.2007.060977
P407
P577
2007-06-28T00:00:00Z