Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription.
about
Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirusInhibitors of human immunodeficiency virus type 1 reverse transcriptase target distinct phases of early reverse transcriptionPrimer tRNAs for reverse transcriptionStructure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors.Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex.Functional domains of Tat required for efficient human immunodeficiency virus type 1 reverse transcription.Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication.Structural basis for the specificity of the initiation of HIV-1 reverse transcription.Initiation of HIV-2 reverse transcription: a secondary structure model of the RNA-tRNA(Lys3) duplex.Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions.Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions.NMR and biochemical characterization of recombinant human tRNA(Lys)3 expressed in Escherichia coli: identification of posttranscriptional nucleotide modifications required for efficient initiation of HIV-1 reverse transcription.Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complexAssembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex.Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription.Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase.A mutant tat protein inhibits HIV-1 reverse transcription by targeting the reverse transcription complex.Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.Genetic encoding of DNA nanostructures and their self-assembly in living bacteria.Human immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.Does the HIV-1 primer activation signal interact with tRNA3(Lys) during the initiation of reverse transcription?Initiation of HIV Reverse TranscriptionInitiation of HIV reverse transcription: is enzyme flipping required?Roles of the human immunodeficiency virus type 1 nucleocapsid protein in annealing and initiation versus elongation in reverse transcription of viral negative-strand strong-stop DNADeletion mutagenesis downstream of the 5' long terminal repeat of human immunodeficiency virus type 1 is compensated for by point mutations in both the U5 region and gag gene.The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription.Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity.Structure-function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primerQuantification of the effects on viral DNA synthesis of reverse transcriptase mutations conferring human immunodeficiency virus type 1 resistance to nucleoside analogues.Functional differences between the human LINE retrotransposon and retroviral reverse transcriptases for in vivo mRNA reverse transcriptionConnection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.Architecture of an HIV-1 reverse transcriptase initiation complex.
P2860
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P2860
Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Binding and kinetic properties ...... tion of reverse transcription.
@ast
Binding and kinetic properties ...... tion of reverse transcription.
@en
type
label
Binding and kinetic properties ...... tion of reverse transcription.
@ast
Binding and kinetic properties ...... tion of reverse transcription.
@en
prefLabel
Binding and kinetic properties ...... tion of reverse transcription.
@ast
Binding and kinetic properties ...... tion of reverse transcription.
@en
P2093
P2860
P1433
P1476
Binding and kinetic properties ...... ation of reverse transcription
@en
P2093
B Ehresmann
C Ehresmann
J M Lanchy
S F Le Grice
P2860
P304
P356
10.1002/J.1460-2075.1996.TB01109.X
P407
P577
1996-12-01T00:00:00Z