Characterization of heparin-binding site of tissue transglutaminase: its importance in cell surface targeting, matrix deposition, and cell signaling.
about
Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Role of transglutaminase 2 in celiac disease pathogenesisTransglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain.Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis.The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion propertiesThe role of TG2 in regulating S100A4-mediated mammary tumour cell migrationActivity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange.Matrix expansion and syncytial aggregation of syndecan-1+ cells underpin villous atrophy in coeliac disease.Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.Dermatan sulfate is a player in the transglutaminase 2 interaction network.Regulation of the activities of the mammalian transglutaminase family of enzymes.Expression of Functional Recombinant Human Tissue Transglutaminase (TG2) Using the Bac-to-Bac Baculovirus Expression SystemSenescence and programmed cell death in plants: polyamine action mediated by transglutaminase.The plant extracellular transglutaminase: what mammal analogues tell.Transglutaminase 2 and neuroinflammation.Transglutaminase inhibitors: a patent review.Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cellsRole of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes.Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosisInvolvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten.Interplay between transglutaminases and heparan sulphate in progressive renal scarring.Transglutaminase 2 in human diseases.The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition.Transglutaminase 2 in cartilage homoeostasis: novel links with inflammatory osteoarthritis.Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2.Soluble Syndecan-1: A Novel Biomarker of Small Bowel Mucosal Damage in Children with Celiac Disease.Proteomic Profiling Reveals the Transglutaminase-2 Externalization Pathway in Kidneys after Unilateral Ureteric Obstruction.Inhibition or ablation of transglutaminase 2 impairs astrocyte migration.Cross-linking of collagen I by tissue transglutaminase provides a promising biomaterial for promoting bone healing.Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor.
P2860
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P2860
Characterization of heparin-binding site of tissue transglutaminase: its importance in cell surface targeting, matrix deposition, and cell signaling.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Characterization of heparin-bi ...... eposition, and cell signaling.
@ast
Characterization of heparin-bi ...... eposition, and cell signaling.
@en
type
label
Characterization of heparin-bi ...... eposition, and cell signaling.
@ast
Characterization of heparin-bi ...... eposition, and cell signaling.
@en
prefLabel
Characterization of heparin-bi ...... eposition, and cell signaling.
@ast
Characterization of heparin-bi ...... eposition, and cell signaling.
@en
P2093
P2860
P356
P1476
Characterization of heparin-bi ...... eposition, and cell signaling.
@en
P2093
Daniel L Rathbone
Kamila Pytel
Martin Griffin
Russell J Collighan
Xiaoling Li
P2860
P304
13063-13083
P356
10.1074/JBC.M111.294819
P407
P577
2012-02-01T00:00:00Z