Identification of a chloride ion binding site in Na+/Cl -dependent transporters. - Wikidata - awgldk - TriplyDB

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

http://www.wikidata.org/entity/Q35921659

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LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake X-ray structure of dopamine transporter elucidates antidepressant mechanism Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures Monoamine transporters: insights from molecular dynamics simulations Insights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDAT Designing modulators of monoamine transporters using virtual screening techniques How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue Structural basis for action by diverse antidepressants on biogenic amine transporters The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors Ligand binding in the conserved interhelical loop of CorA, a magnesium transporter from Mycobacterium tuberculosis Outcome of a workshop on applications of protein models in biomedical research Mutations in the GlyT2 gene (SLC6A5) are a second major cause of startle disease.Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters.Substrate-dependent proton antiport in neurotransmitter:sodium symporters.Expression, purification and structural analysis of functional GABA transporter 1 using the baculovirus expression system.Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter.The N terminus of monoamine transporters is a lever required for the action of amphetamines The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter.Comparison of human solute carriers Conformational flexibility of transmembrane helix VII of the human serotonin transporter impacts ion dependence and transport.The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue.Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.The second sodium site in the dopamine transporter controls cation permeation and is regulated by chloride.Cytoplasmic permeation pathway of neurotransmitter transporters.GATMD: γ-aminobutyric acid transporter mutagenesis database.Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site.X-ray structures and mechanism of the human serotonin transporter.Halorhodopsin pumps Cl- and bacteriorhodopsin pumps protons by a common mechanism that uses conserved electrostatic interactions.Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model SLC6 transporters: structure, function, regulation, disease association and therapeutics The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters Homology modeling of human γ-butyric acid transporters and the binding of pro-drugs 5-aminolevulinic acid and methyl aminolevulinic acid used in photodynamic therapy.Microseconds simulations reveal a new sodium-binding site and the mechanism of sodium-coupled substrate uptake by LeuT Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

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P2860

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

http://www.wikidata.org/entity/Q35921659

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

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Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

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type

label

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

@ast

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

@en

prefLabel

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

@ast

Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Identification of a chloride ion binding site in Na+/Cl -dependent transporters

@en

P2093

Barry Honig

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Gary Rudnick

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Sotiria Tavoulari

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Yuan-Wei Zhang

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P2860

Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain

The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2)

MUSCLE: multiple sequence alignment with high accuracy and high throughput

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

Structure of the light-driven chloride pump halorhodopsin at 1.8 A resolution

X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

Recognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transporters

Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

An assessment of the accuracy of methods for predicting hydrogen positions in protein structures.

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