ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. - Wikidata - awgldk - TriplyDB

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

http://www.wikidata.org/entity/Q35921685

about

Genome-wide identification, characterization and phylogenetic analysis of 50 catfish ATP-binding cassette (ABC) transporter genes TMEM14C is required for erythroid mitochondrial heme metabolism Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein.Missense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia.Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi Role of heme in cardiovascular physiology and disease.Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver.Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR).ABCB6 mRNA and DNA methylation levels serve as useful biomarkers for prediction of early intrahepatic recurrence of hepatitis C virus-related hepatocellular carcinoma.Novel hematopoietic target genes in the NRF2-mediated transcriptional pathway.The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6.Efficient purification and reconstitution of ATP binding cassette transporter B6 (ABCB6) for functional and structural studies Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes.Heme and erythropoieis: more than a structural role.ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.ABCB6, an ABC Transporter Impacting Drug Response and Disease.Hereditary stomatocytosis: An underdiagnosed condition.ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia.Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite

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P2860

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

http://www.wikidata.org/entity/Q35921685

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

@ast

ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

@en

type

label

ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

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ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

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prefLabel

ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

@ast

ATP-dependent mitochondrial po ...... inst phenylhydrazine toxicity.

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P356

JBC.M111.336180

P1433

Journal of Biological Chemistry

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ATP-dependent mitochondrial po ...... ainst phenylhydrazine toxicity

@en

P2093

Dagny L Ulrich

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Daxi Sun

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Deepa Nachagari

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Guoqing Du

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Jerold E Rehg

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John D Schuetz

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John Lynch

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Lyudmila Tsurkan

http://www.w3.org/2001/XMLSchema#string

Yao Wang

http://www.w3.org/2001/XMLSchema#string

Yiping Fan

http://www.w3.org/2001/XMLSchema#string

P2860

Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6

Identification of a mammalian mitochondrial porphyrin transporter

Adenine nucleotide translocator transports haem precursors into mitochondria

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins

A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

Transcriptional regulation of the murine erythroid-specific 5-aminolevulinate synthase gene

Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2

The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability

An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria

P304

12679-12690

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scholarly article

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10.1074/JBC.M111.336180

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16

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287

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Philip M Potter

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2012-01-31T00:00:00Z

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22294697

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3339991

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