Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.
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Human liver mitochondrial cytochrome P450 2D6--individual variations and implications in drug metabolismTricyclic antidepressant pharmacology and therapeutic drug interactions updatedRevealing the paradox of drug reward in human evolutionPharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapyPain Management of Pediatric Musculoskeletal Injury in the Emergency Department: A Systematic ReviewHepatotoxicity Induced by "the 3Ks": Kava, Kratom and KhatThe pharmacogenomics of pain management: prospects for personalized medicinePotential drug-drug interactions in Alzheimer patients with behavioral symptomsPharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineCYP2D6 polymorphisms and their influence on risperidone treatmentA Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline PharmacotherapyIdentification of new alleles and the determination of alleles and genotypes frequencies at the CYP2D6 gene in EmiratisMolecular dynamics of CYP2D6 polymorphisms in the absence and presence of a mechanism-based inactivator reveals changes in local flexibility and dominant substrate access channelsDistribution of CYP2D6 alleles and phenotypes in the Brazilian populationWhere Failure Is Not an Option -Personalized Medicine in AstronautsVariation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax RelapsesImmunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extractProgress towards the integration of pharmacogenomics in practiceCYP2D6 genotyping and tamoxifen: an unfinished story in the quest for personalized medicine.Understanding the determinants of selectivity in drug metabolism through modeling of dextromethorphan oxidation by cytochrome P450.Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing data.Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.Multiplex genotyping of CYP3A4, CYP3A5, CYP2C9 and CYP2C19 SNPs using MALDI-TOF mass spectrometry.Pharmacogenetic testing revisited: 5' nuclease real-time polymerase chain reaction test panels for genotyping CYP2D6 and CYP2C19.Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort studyThe Impact of CYP2D6 Genotyping on Tamoxifen TreatmentTowards the clinical implementation of pharmacogenetics in bipolar disorder.Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.RNA-Seq analysis implicates detoxification pathways in ovine mycotoxin resistanceEffects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention.Tailoring adjuvant endocrine therapy for postmenopausal breast cancer: a CYP2D6 multiple-genotype-based modeling analysis and validation.Evaluation of cytochrome P450 2D6 phenotyping in healthy adult Western IndiansCYP2D6: novel genomic structures and alleles.Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy.The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness.CYP2D6 in the metabolism of opioids for mild to moderate pain.Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo.A mechanistic insight into 3,4-methylenedioxymethamphetamine ("ecstasy")-mediated hepatotoxicity.Genotyping of DNA samples isolated from formalin-fixed paraffin-embedded tissues using preamplification.Gene and protein expression and cellular localisation of cytochrome P450 enzymes of the 1A, 2A, 2C, 2D and 2E subfamilies in equine intestine and liver.
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P2860
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@ast
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@en
type
label
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@ast
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@en
prefLabel
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@ast
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@en
P356
P1476
Genetic polymorphisms of cytoc ...... ects and functional diversity.
@en
P2093
Ingelman-Sundberg M
P2888
P356
10.1038/SJ.TPJ.6500285
P577
2005-01-01T00:00:00Z