Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.
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G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsFunctional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon TransportPosttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses.Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel functionCorticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease.Tau protein is essential for stress-induced brain pathologyCorticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling.Targeting psychologic stress signaling pathways in Alzheimer's disease.Abnormal dendritic maturation of developing cortical neurons exposed to corticotropin releasing hormone (CRH): Insights into effects of prenatal adversity?Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor.Stress during a critical postnatal period induces region-specific structural abnormalities and dysfunction of the prefrontal cortex via CRF1.Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease.The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activityCorticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model.Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor.Reproductive Stage and Modulation of Stress-Induced Tau Phosphorylation in Female Rats.Locus Coeruleus, norepinephrine and Aβ peptides in Alzheimer's diseaseShort-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD miceDynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis.Reconsidering Animal Models of Major Depressive Disorder in the Elderly.Sex-biased cellular signaling: molecular basis for sex differences in neuropsychiatric diseases.Death by a thousand cuts in Alzheimer's disease: hypoxia--the prodrome.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Neurotoxic saboteurs: straws that break the hippo's (hippocampus) back drive cognitive impairment and Alzheimer's Disease.Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD.Environmental factors in the development and progression of late-onset Alzheimer's disease."Boomerang Neuropathology" of Late-Onset Alzheimer's Disease is Shrouded in Harmful "BDDS": Breathing, Diet, Drinking, and Sleep During Aging.Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.The CRF System as a Therapeutic Target for Neuropsychiatric Disorders.Exaggerated phosphorylation of brain tau protein in CRH KO mice exposed to repeated immobilization stress.Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation.Stress induced neural reorganization: A conceptual framework linking depression and Alzheimer's disease.Early postnatal stress suppresses the developmental trajectory of hippocampal pyramidal neurons: the role of CRHR1.Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats.Blockade of corticotropin-releasing hormone receptor 1 attenuates early-life stress-induced synaptic abnormalities in the neonatal hippocampus.Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid.Impact of the Relationship of Stress and the Immune System in the Appearance of Alzheimer's Disease.Sex differences in chronic stress responses and Alzheimer's disease.The relationship between stress and Alzheimer's disease.
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P2860
Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Corticotropin-releasing factor ...... , solubility, and aggregation.
@ast
Corticotropin-releasing factor ...... , solubility, and aggregation.
@en
type
label
Corticotropin-releasing factor ...... , solubility, and aggregation.
@ast
Corticotropin-releasing factor ...... , solubility, and aggregation.
@en
prefLabel
Corticotropin-releasing factor ...... , solubility, and aggregation.
@ast
Corticotropin-releasing factor ...... , solubility, and aggregation.
@en
P2093
P2860
P356
P1476
Corticotropin-releasing factor ...... , solubility, and aggregation.
@en
P2093
Allyson Roe Lee
Kenner C Rice
Michael A Staup
Nicholas J Justice
Paul E Sawchenko
Robert A Rissman
P2860
P304
P356
10.1073/PNAS.1203140109
P407
P50
P577
2012-03-26T00:00:00Z