Neutral sphingomyelinase (SMPD3) deficiency causes a novel form of chondrodysplasia and dwarfism that is rescued by Col2A1-driven smpd3 transgene expression
about
An overview of sphingolipid metabolism: from synthesis to breakdownPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsInhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice.Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology.Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation.Choline kinase beta is required for normal endochondral bone formationComparative epigenomics of human and mouse mammary tumors.Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDLA cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.Comparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI.Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development.Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition.Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.The roles of neutral sphingomyelinases in neurological pathologies.Sphingolipid metabolism and neutral sphingomyelinases.Sphingolipid metabolism and its role in the skeletal tissues.Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanismSphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells.Local regulation of tooth mineralization by sphingomyelin phosphodiesterase 3.Identification and evaluation of neutral sphingomyelinase 2 inhibitors.SMPD3 deficiency perturbs neuronal proteostasis and causes progressive cognitive impairment.
P2860
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P2860
Neutral sphingomyelinase (SMPD3) deficiency causes a novel form of chondrodysplasia and dwarfism that is rescued by Col2A1-driven smpd3 transgene expression
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@ast
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@en
type
label
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@ast
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@en
prefLabel
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@ast
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@en
P2093
P2860
P1476
Neutral sphingomyelinase (SMPD ...... ven smpd3 transgene expression
@en
P2093
Anja Niehoff
Barbara Holz
Britta Jenke
Erika Binczek
Jutta Knifka
Jürgen Koebke
Robert Heinz Günter
Wilhelm Stoffel
P2860
P304
P356
10.2353/AJPATH.2007.061285
P407
P577
2007-07-01T00:00:00Z