Combining Foxc2 and Connexin37 deletions in mice leads to severe defects in lymphatic vascular growth and remodeling.
about
Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valvesGap junctional signaling in pattern regulation: Physiological network connectivity instructs growth and form.Connexins and their channels in inflammation.Inhibitors of connexin and pannexin channels as potential therapeutics.Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function.Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Intraluminal valves: development, function and disease.Human venous valve disease caused by mutations in FOXC2 and GJC2.Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43.Mechanisms of Connexin-Related Lymphedema
P2860
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P2860
Combining Foxc2 and Connexin37 deletions in mice leads to severe defects in lymphatic vascular growth and remodeling.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@ast
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@en
type
label
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@ast
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@en
prefLabel
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@ast
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@en
P2093
P2860
P1476
Combining Foxc2 and Connexin37 ...... ascular growth and remodeling.
@en
P2093
Alexander M Simon
John D Kanady
Marlys H Witte
Stephanie J Munger
P2860
P356
10.1016/J.YDBIO.2015.06.004
P407
P577
2015-06-14T00:00:00Z