The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities.
about
Protein tyrosine phosphatase alpha (PTPalpha) and contactin form a novel neuronal receptor complex linked to the intracellular tyrosine kinase fynA phosphotyrosine displacement mechanism for activation of Src by PTPalphaPhosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivoActivation of Src and transformation by an RPTPα splice mutant found in human tumoursA human transmembrane protein-tyrosine-phosphatase, PTP zeta, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrasesThe second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigmaTight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domainsReceptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiationThe Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseTwo mechanisms activate PTPalpha during mitosisCD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytesSubstrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathwayRole of PTPα in the destruction of periodontal connective tissuesclr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans.Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlar in vivo.Receptor type protein tyrosine phosphatases (RPTPs) - roles in signal transduction and human disease.RPTPalpha is essential for NCAM-mediated p59fyn activation and neurite elongation.Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling.The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulationProtein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.Extracellular regulation of type IIa receptor protein tyrosine phosphatases: mechanistic insights from structural analyses.Regulation of receptor protein-tyrosine phosphatase alpha by oxidative stress.Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides.Overexpression of leucocyte common antigen (LAR) P-subunit in thyroid carcinomas.
P2860
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P2860
The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The receptor-like protein tyro ...... tinct substrate specificities.
@ast
The receptor-like protein tyro ...... tinct substrate specificities.
@en
type
label
The receptor-like protein tyro ...... tinct substrate specificities.
@ast
The receptor-like protein tyro ...... tinct substrate specificities.
@en
prefLabel
The receptor-like protein tyro ...... tinct substrate specificities.
@ast
The receptor-like protein tyro ...... tinct substrate specificities.
@en
P2860
P1433
P1476
The receptor-like protein tyro ...... tinct substrate specificities.
@en
P2093
P2860
P304
P407
P577
1991-11-01T00:00:00Z