Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype. - Wikidata - awgldk - TriplyDB

Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype.

Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype.

http://www.wikidata.org/entity/Q35935919

about

Hallmarks of cancer and AU-rich elements Post-transcriptional Regulation of Immunological Responses through Riboclustering The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases Global analysis of posttranscriptional gene expression in response to sodium arsenite Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.Tristetraprolin expression by keratinocytes controls local and systemic inflammation.Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation TNF and MAP kinase signalling pathways.Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages.Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease.Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.Spontaneous retrotransposon insertion into TNF 3'UTR causes heart valve disease and chronic polyarthritis.Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies.LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action.Tristetraprolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory disease A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system Suppression of IL-12 production by tristetraprolin through blocking NF-kcyB nuclear translocation.Life without TTP: apparent absence of an important anti-inflammatory protein in birds Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection.Post-transcriptional coordination of immunological responses by RNA-binding proteins.Post-transcriptional gene regulation by RNA-binding proteins in vascular endothelial dysfunction.Identification of quantitative trait transcripts for growth traits in the large scales of liver and muscle samples.RNA binding proteins as regulators of immune cell biology.Tristetraprolin as a Therapeutic Target in Inflammatory Disease RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins.An Ancient Family of RNA-Binding Proteins: Still Important!p38 MAPK/PP2Acα/TTP pathway on the connection of TNF-α and caspases activation on hydroquinone-induced apoptosis.Beta Interferon Production Is Regulated by p38 Mitogen-Activated Protein Kinase in Macrophages via both MSK1/2- and Tristetraprolin-Dependent Pathways.The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.Quaking Deficiency Amplifies Inflammation in Experimental Endotoxemia via the Aryl Hydrocarbon Receptor/Signal Transducer and Activator of Transcription 1-NF-κB Pathway.A knock-in tristetraprolin (TTP) zinc finger point mutation in mice: Comparison with complete TTP deficiency.Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland.

P2860

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P2860

Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype.

http://www.wikidata.org/entity/Q35935919

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

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P356

JIMMUNOL.1103700

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Journal of Immunology

P1476

Myeloid-specific tristetraprol ...... n otherwise minimal phenotype.

@en

P2093

Deborah J Stumpo

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Lian-Qun Qiu

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Perry J Blackshear

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P2860

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNA

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis

Tristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonuclease

A new mathematical model for relative quantification in real-time RT-PCR

Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein

A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence

HuR as a negative posttranscriptional modulator in inflammation

Roles of tumor necrosis factor-alpha receptor subtypes in the pathogenesis of the tristetraprolin-deficiency syndrome

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5150-5159

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10.4049/JIMMUNOL.1103700

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10

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188

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2012-04-09T00:00:00Z

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223972725

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22491258

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lipopolysaccharide

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3345041

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