Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6
about
Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1Ubiquitin-like protein MNSFβ covalently binds to Bcl-G and enhances lipopolysaccharide/interferon γ-induced apoptosis in macrophagesDisruption of FAT10-MAD2 binding inhibits tumor progression.Structural and functional insights to ubiquitin-like protein conjugation.Ufmylation and FATylation pathways are downregulated in human alcoholic and nonalcoholic steatohepatitis, and mice fed DDC, where Mallory-Denk bodies (MDBs) formConjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage displayUbiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivin.Mechanistic study of Uba5 enzyme and the Ufm1 conjugation pathway.Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation MachineryA small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
P2860
Q24337322-DB1C0793-66D9-433F-B220-2C28C67596F1Q28589126-1B50D42E-45C7-4A77-9AFA-0956912A92F1Q31814836-6CFF8C36-DF4A-4B98-8FFD-BF0DC9F0FFC7Q33987001-D4C7AEF5-72CC-4B7C-9CFC-9318AC82E5BFQ34022720-9C0CDDB4-6F2C-4609-810C-4D4641B4BA31Q34467024-F9707447-D761-4306-8E61-0A3A23E3449BQ36298709-51614E9B-FF9A-4229-977B-55E693DC3AE1Q37697183-C5841BE3-6399-4B37-BA2D-0FC7B8034251Q38981169-9A5C5457-DE28-425E-9199-94129730747DQ39149390-15567848-721D-490F-BF0D-845259B76F6BQ40336938-892D2DCB-2089-4B0D-8252-ED4CD8CA3891Q48243218-425ADDE6-84F8-47F1-8977-4C8A201C5CA7
P2860
Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@ast
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@en
type
label
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@ast
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@en
prefLabel
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@ast
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@en
P2093
P2860
P356
P1476
Mechanistic studies on activat ...... fier activating enzyme 6, Uba6
@en
P2093
Alexandra E Gould
Benjamin S Amidon
Huay-Keng Loke
James E Brownell
James M Gavin
Jesse J Chen
Lawrence R Dick
Neil Rollins
P2860
P304
15512-15522
P356
10.1074/JBC.M111.336198
P407
P577
2012-03-15T00:00:00Z