about
Molecular functions of thyroid hormones and their clinical significance in liver-related diseasesA role of histone H3 lysine 4 methyltransferase components in endosomal traffickingCathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cellsPreclinical efficacy of cystatin C to target the oncogenic activity of transforming growth factor Beta in breast cancerMegakaryocytes, malignancy and bone marrow vascular nichesA mouse stromal response to tumor invasion predicts prostate and breast cancer patient survivalThe invasion and metastasis promotion role of CD97 small isoform in gastric carcinomaNon-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probeTopical application of activity-based probes for visualization of brain tumor tissueLysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts.Novel peptidyl aryl vinyl sulfones as highly potent and selective inhibitors of cathepsins L and B.How does heparin prevent the pH inactivation of cathepsin B? Allosteric mechanism elucidated by docking and molecular dynamicsDistinct roles for cysteine cathepsin genes in multistage tumorigenesisIdentification of modulated genes by three classes of chemopreventive agents at preneoplastic stages in a p53-null mouse mammary tumor modelDiagnostic values of serum cathepsin B and D in patients with nasopharyngeal carcinoma.Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.Cathepsin B inhibition limits bone metastasis in breast cancer.JNK2 is activated during ER stress and promotes cell survivalThe importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.The metastatic niche: adapting the foreign soil.Immune cells as mediators of solid tumor metastasis.Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.Silencing of atp6v1c1 prevents breast cancer growth and bone metastasis.Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.Cathepsins mediate tumor metastasis.Cancer-associated lysosomal changes: friends or foes?Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.Effects of Vacuolar H(+)-ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA-MB231 Breast Cancer Cells.Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.IGF-1 promotes the growth and metastasis of hepatocellular carcinoma via the inhibition of proteasome-mediated cathepsin B degradation.p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3Cathepsins in digestive cancers.Cathepsin K expression and activity in canine osteosarcoma.Inhibitory effect of the sugarcane cystatin CaneCPI-4 on cathepsins B and L and human breast cancer cell invasion.Chemotherapy-induced mucositis is associated with changes in proteolytic pathways.Addition of 2-(ethylamino)acetonitrile group to nitroxoline results in significantly improved anti-tumor activity in vitro and in vivoThe S2 subsites of cathepsins K and L and their contribution to collagen degradation.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Multiple roles for cysteine cathepsins in cancer.
@ast
Multiple roles for cysteine cathepsins in cancer.
@en
type
label
Multiple roles for cysteine cathepsins in cancer.
@ast
Multiple roles for cysteine cathepsins in cancer.
@en
prefLabel
Multiple roles for cysteine cathepsins in cancer.
@ast
Multiple roles for cysteine cathepsins in cancer.
@en
P356
P1433
P1476
Multiple roles for cysteine cathepsins in cancer.
@en
P2093
Douglas Hanahan
Johanna A Joyce
P304
P356
10.4161/CC.3.12.1289
P577
2004-12-06T00:00:00Z