Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis.
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Do the A subunits contribute to the differences in the toxicity of Shiga toxin 1 and Shiga toxin 2?Elongation factor G bound to the ribosome in an intermediate state of translocation.Structural studies on a non-toxic homologue of type II RIPs from bitter gourd: Molecular basis of non-toxicity, conformational selection and glycan structureVapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNAThe A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1.Functional divergence between the two P1-P2 stalk dimers on the ribosome in their interaction with ricin A chainHuman ribosomal P1-P2 heterodimer represents an optimal docking site for ricin A chain with a prominent role for P1 C-terminus.Picazoplatin, an azide-containing platinum(II) derivative for target analysis by click chemistry.EF-G and EF4: translocation and back-translocation on the bacterial ribosome.Free-energy landscape of reverse tRNA translocation through the ribosome analyzed by electron microscopy density maps and molecular dynamics simulations.Role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis.Universal and domain-specific sequences in 23S-28S ribosomal RNA identified by computational phylogeneticsTargeting ricin to the ribosome.Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalkConserved Arginines at the P-Protein Stalk Binding Site and the Active Site Are Critical for Ribosome Interactions of Shiga Toxins but Do Not Contribute to Differences in the Affinity of the A1 Subunits for the Ribosome.Quality control mechanisms during ribosome maturation.Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome.Expression of distinct maternal and somatic 5.8S, 18S, and 28S rRNA types during zebrafish development.GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner.Sequence comparison and phylogenetic analysis by the Maximum Likelihood method of ribosome-inactivating proteins from angiosperms.Platinum-RNA modifications following drug treatment in S. cerevisiae identified by click chemistry and enzymatic mapping.Toxins MazF and MqsR cleave Escherichia coli rRNA precursors at multiple sites.Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides.The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.
P2860
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P2860
Functional role of the sarcin-ricin loop of the 23S rRNA in the elongation cycle of protein synthesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Functional role of the sarcin- ...... on cycle of protein synthesis.
@ast
Functional role of the sarcin- ...... on cycle of protein synthesis.
@en
type
label
Functional role of the sarcin- ...... on cycle of protein synthesis.
@ast
Functional role of the sarcin- ...... on cycle of protein synthesis.
@en
prefLabel
Functional role of the sarcin- ...... on cycle of protein synthesis.
@ast
Functional role of the sarcin- ...... on cycle of protein synthesis.
@en
P2093
P2860
P1476
Functional role of the sarcin- ...... on cycle of protein synthesis.
@en
P2093
Karissa Y Sanbonmatsu
Prashant K Khade
Simpson Joseph
Xinying Shi
P2860
P304
P356
10.1016/J.JMB.2012.03.016
P407
P577
2012-03-26T00:00:00Z