Biophysical alterations of hippocampal pyramidal neurons in learning, ageing and Alzheimer's disease.
about
Hyperpolarization-activated current (In) is reduced in hippocampal neurons from Gabra5-/- mice.CAMKII activation is not required for maintenance of learning-induced enhancement of neuronal excitabilityHippocalcin: a new solution to an old puzzle.Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation.Estrogen and hippocampal plasticity in rodent models.Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms.Redox sensitive calcium stores underlie enhanced after hyperpolarization of aged neurons: role for ryanodine receptor mediated calcium signalingDynamic interplay of excitatory and inhibitory coupling modes of neuronal L-type calcium channels.Bidirectional pattern-specific plasticity of the slow afterhyperpolarization in rats: role for high-voltage activated Ca2+ channels and I h.Environmental enrichment decreases the afterhyperpolarization in senescent rats.Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticityExpansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store.Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel gene Cacna1c (Cav 1.2)Hippocalcin and KCNQ channels contribute to the kinetics of the slow afterhyperpolarization.What determines the kinetics of the slow afterhyperpolarization (sAHP) in neurons?Memantine in the treatment of mild-to-moderate Alzheimer's disease.Calcium homeostasis and modulation of synaptic plasticity in the aged brain.Long-lasting neural circuit dysfunction following developmental ethanol exposureElectrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release.L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.CA1 pyramidal cells have diverse biophysical properties, affected by development, experience, and agingSynergistic actions of metabotropic acetylcholine and glutamate receptors on the excitability of hippocampal CA1 pyramidal neurons.Pituitary adenylate cyclase-activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sIAHP in CA1 pyramidal neurons by activating multiple signaling pathways.Different involvement of type 1, 2, and 3 ryanodine receptors in memory processesInput-to-output transformation in a model of the rat hippocampal CA1 network.Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077).Temporal binding function of dorsal CA1 is critical for declarative memory formation.Peripheral and central administration of T3 improved the histological changes, memory and the dentate gyrus electrophysiological activity in an animal model of Alzheimer's disease.Differential contributions of Ca2+ -activated K+ channels and Na+ /K+ -ATPases to the generation of the slow afterhyperpolarization in CA1 pyramidal cells.Stability and plasticity of intrinsic membrane properties in hippocampal CA1 pyramidal neurons: effects of internal anions.
P2860
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P2860
Biophysical alterations of hippocampal pyramidal neurons in learning, ageing and Alzheimer's disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@ast
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@en
type
label
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@ast
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@en
prefLabel
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@ast
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@en
P2093
P1476
Biophysical alterations of hip ...... geing and Alzheimer's disease.
@en
P2093
John F Disterhoft
Masuo Ohno
Wendy W Wu
P304
P356
10.1016/J.ARR.2004.07.001
P577
2004-11-01T00:00:00Z