An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.
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Development of Novel Vaccines against Enterovirus-71Quantification of viral infection dynamics in animal experimentsProduction of EV71 vaccine candidatesEV-A71 vaccine licensure: a first step for multivalent enterovirus vaccine to control HFMD and other severe diseasesTherapeutic and prevention strategies against human enterovirus 71 infectionImmunological and biochemical characterization of coxsackie virus A16 viral particlesEnterovirus 71 infection and vaccines.Animal models of enterovirus 71 infection: applications and limitations.Immunization of N terminus of enterovirus 71 VP4 elicits cross-protective antibody responses.Recombinant tandem multi-linear neutralizing epitopes of human enterovirus 71 elicited protective immunity in miceEvolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 geneThe cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments.Analysis of cross-reactive neutralizing antibodies in human HFMD serum with an EV71 pseudovirus-based assay.Cryo-electron microscopy study of insect cell-expressed enterovirus 71 and coxsackievirus a16 virus-like particles provides a structural basis for vaccine development.Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system.Monitoring antigenic variations of enterovirus 71: implications for virus surveillance and vaccine developmentDisplay of VP1 on the surface of baculovirus and its immunogenicity against heterologous human enterovirus 71 strains in miceLong-term immunogenicity studies of formalin-inactivated enterovirus 71 whole-virion vaccine in macaques.Identification of site-specific adaptations conferring increased neural cell tropism during human enterovirus 71 infectionComparative analysis of the immunogenicity and protective effects of inactivated EV71 vaccines in mice.Cross-reactive neutralizing antibody responses to enterovirus 71 infections in young children: implications for vaccine development.Antibody dependent enhancement infection of enterovirus 71 in vitro and in vivo.The cross-neutralizing activity of enterovirus 71 subgenotype c4 vaccines in healthy chinese infants and children.The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey ModelImmunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations.Molecular determinants of enterovirus 71 viral entry: cleft around GLN-172 on VP1 protein interacts with variable region on scavenge receptor B 2.Cooperative effect of the attenuation determinants derived from poliovirus sabin 1 strain is essential for attenuation of enterovirus 71 in the NOD/SCID mouse infection model.EV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challengeEnteroviruses in the early 21st century: new manifestations and challengesRational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditionsNecrotizing myositis causes restrictive hypoventilation in a mouse model for human enterovirus 71 infectionCooperative effect of the VP1 amino acids 98E, 145A and 169F in the productive infection of mouse cell lines by enterovirus 71 (BS strain).Reemergence of enterovirus 71 in 2008 in taiwan: dynamics of genetic and antigenic evolution from 1998 to 2008.Progress on the research and development of inactivated EV71 whole-virus vaccines.Human enterovirus 71 and hand, foot and mouth disease.Development of enterovirus 71 vaccines.Cell and tissue tropism of enterovirus 71 and other enteroviruses infectionsThe virology and developments toward control of human enterovirus 71.Scavenger receptor b2 as a receptor for hand, foot, and mouth disease and severe neurological diseases.Progress on the research and development of human enterovirus 71 (EV71) vaccines.
P2860
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P2860
An attenuated strain of enterovirus 71 belonging to genotype a showed a broad spectrum of antigenicity with attenuated neurovirulence in cynomolgus monkeys.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@ast
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@en
type
label
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@ast
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@en
prefLabel
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@ast
An attenuated strain of entero ...... rulence in cynomolgus monkeys.
@en
P2093
P2860
P356
P1433
P1476
An attenuated strain of entero ...... irulence in cynomolgus monkeys
@en
P2093
Hiroyuki Shimizu
Katsumi Mizuta
Naoko Iwata
Noriyo Nagata
Takaji Wakita
Takuya Iwasaki
Yasushi Ami
Yuriko Suzaki
P2860
P304
P356
10.1128/JVI.02856-06
P407
P577
2007-06-13T00:00:00Z