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Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivoImmunotherapy strategies for multiple myeloma: the present and the futureLymphoma incidence patterns by WHO subtype in the United States, 1992-2001Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myelomaPhase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome.MYC Deregulation in Primary Human Cancers.NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma.Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma.A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cellsMass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma.Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis.Proteasome inhibition as a therapeutic strategy for hematologic malignancies.Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma.Immune response to premalignancy: insights from patients with monoclonal gammopathy.Loss of p53 exacerbates multiple myeloma phenotype by facilitating the reprogramming of hematopoietic stem/progenitor cells to malignant plasma cells by MafB.Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomasRole of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma.A review of lenalidomide in combination with dexamethasone for the treatment of multiple myeloma.IRF4 addiction in multiple myelomaInteractions of the Hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib.Preclinical studies of novel targeted therapies.TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity.From the bench to the bedside: emerging new treatments in multiple myeloma.Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity.The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptorFrequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.Risk of vertebral compression fractures in multiple myeloma patients: A finite-element study.Diffuse large B cell lymphoma in hyper-IgE syndrome due to STAT3 mutation.Role and regulation of CD1d in normal and pathological B cells.Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma.A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment.Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line.Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression.Correlation of high-resolution X-ray micro-computed tomography with bioluminescence imaging of multiple myeloma growth in a xenograft mouse model.Clonal Expansion and Interrelatedness of Distinct B-Lineage Compartments in Multiple Myeloma Bone Marrow.BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Focus on multiple myeloma.
@ast
Focus on multiple myeloma.
@en
type
label
Focus on multiple myeloma.
@ast
Focus on multiple myeloma.
@en
prefLabel
Focus on multiple myeloma.
@ast
Focus on multiple myeloma.
@en
P2093
P1433
P1476
Focus on multiple myeloma.
@en
P2093
Constantine S Mitsiades
Nicholas Mitsiades
Nikhil C Munshi
P304
P356
10.1016/J.CCR.2004.10.020
P577
2004-11-01T00:00:00Z