Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesA systems approach to prion diseaseIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesMetals in obex and retropharyngeal lymph nodes of Illinois white-tailed deer and their variations associated with CWD statusOn the Nature of Tintinnid Loricae (Ciliophora: Spirotricha: Tintinnina): a Histochemical, Enzymatic, EDX, and High-resolution TEM Study.Abnormal brain iron homeostasis in human and animal prion disordersPrion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transportParadoxical role of prion protein aggregates in redox-iron induced toxicity.Prion protein regulates iron transport by functioning as a ferrireductase.Redox control of prion and disease pathogenesis.Iron content of ferritin modulates its uptake by intestinal epithelium: implications for co-transport of prions.Metal and complementary molecular bioimaging in Alzheimer's disease.The distribution of four trace elements (Fe, Mn, Cu, Zn) in forage and the relation to scrapie in IcelandPrion protein promotes kidney iron uptake via its ferrireductase activity.The role of iron in prion disease and other neurodegenerative diseasesInfectious prion protein alters manganese transport and neurotoxicity in a cell culture model of prion disease.Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains.Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication.Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesisAn emerging concept of prion infections as a form of transmissible cerebral amyloidosis.Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunitiesDe novo mammalian prion synthesis.Metal attenuating therapies in neurodegenerative disease.Role of lipid in forming an infectious prion?Iron in neurodegenerative disorders of protein misfolding: a case of prion disorders and Parkinson's disease.Evaluation of infective property of recombinant prion protein amyloids in cultured cells overexpressing cellular prion protein.Hemin interactions and alterations of the subcellular localization of prion protein.Transcriptional modulation in a leukocyte-depleted splenic cell population during prion disease.No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.
P2860
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P2860
Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Modulation of proteinase K-res ...... ation and disease pathogenesis
@ast
Modulation of proteinase K-res ...... ation and disease pathogenesis
@en
type
label
Modulation of proteinase K-res ...... ation and disease pathogenesis
@ast
Modulation of proteinase K-res ...... ation and disease pathogenesis
@en
prefLabel
Modulation of proteinase K-res ...... ation and disease pathogenesis
@ast
Modulation of proteinase K-res ...... ation and disease pathogenesis
@en
P2093
P2860
P356
P1476
Modulation of proteinase K-res ...... ation and disease pathogenesis
@en
P2093
Bishwajit Kundu
Maradumane L Mohan
Neena Singh
Qingzhong Kong
Subhabrata Basu
P2860
P304
P356
10.1091/MBC.E07-04-0317
P577
2007-06-13T00:00:00Z