Asymmetrical blockade of the Ca2+ release channel (ryanodine receptor) by 12-kDa FK506 binding protein.
about
Further characterization of the type 3 ryanodine receptor (RyR3) purified from rabbit diaphragmA novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptorFAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.FKBP12 binding modulates ryanodine receptor channel gatingDeletion of amino acids 1641-2437 from the foot region of skeletal muscle ryanodine receptor alters the conduction properties of the Ca release channel.Single-channel properties of the recombinant skeletal muscle Ca2+ release channel (ryanodine receptor).Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor.Rectification of skeletal muscle ryanodine receptor mediated by FK506 binding protein.Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.Three-dimensional visualization of FKBP12.6 binding to an open conformation of cardiac ryanodine receptorT-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases.FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stabilityCa2+-operated transcriptional networks: molecular mechanisms and in vivo models.Ryanodine receptor-mediated arrhythmias and sudden cardiac death.Effect of luminal calcium on Ca2+ release channel activity of sarcoplasmic reticulum in situ.DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor.Augmentation of SR Ca(2+) release by rapamycin and FK506 causes K(+)-channel activation and membrane hyperpolarization in bladder smooth muscle.Single-channel kinetics, inactivation, and spatial distribution of inositol trisphosphate (IP3) receptors in Xenopus oocyte nucleus.Protein-protein interactions in intracellular Ca2+-release channel function.Neuroprotective effect of immunosuppressant FK506 in transient focal ischemia in rat: therapeutic time window for FK506 in transient focal ischemia.Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms.
P2860
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P2860
Asymmetrical blockade of the Ca2+ release channel (ryanodine receptor) by 12-kDa FK506 binding protein.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@ast
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@en
type
label
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@ast
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@en
prefLabel
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@ast
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@en
P2093
P2860
P356
P1476
Asymmetrical blockade of the C ...... 12-kDa FK506 binding protein.
@en
P2093
P2860
P304
11953-11957
P356
10.1073/PNAS.91.25.11953
P407
P577
1994-12-01T00:00:00Z