Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease

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The amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism.Evaluation of Cu(i) binding to the E2 domain of the amyloid precursor protein - a lesson in quantification of metal binding to proteins via ligand competition.

P2860

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P2860

Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease

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http://www.wikidata.org/entity/Q35950853

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2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Crystallization and preliminar ...... protein of Alzheimer's disease

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Crystallization and preliminar ...... protein of Alzheimer's disease

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Crystallization and preliminar ...... protein of Alzheimer's disease

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Crystallization and preliminar ...... protein of Alzheimer's disease

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Crystallization and preliminar ...... protein of Alzheimer's disease

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Crystallization and preliminar ...... protein of Alzheimer's disease

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P1476

Crystallization and preliminar ...... protein of Alzheimer's disease

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P2093

Denise Galatis

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Galina Polekhina

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Geoffrey K-W Kong

http://www.w3.org/2001/XMLSchema#string

Julian J Adams

http://www.w3.org/2001/XMLSchema#string

Kevin J Barnham

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P2860

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

Solvent content of protein crystals

The CCP4 suite: programs for protein crystallography

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts

Alzheimer's disease is a synaptic failure

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

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scholarly article

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10.1107/S1744309104029744

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Pt 1

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2004-12-02T00:00:00Z

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16508101

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Alzheimer's disease

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1952382

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Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease

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P2860

P2860

Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P921

P932