PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation
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HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathwayThe Rac1 polybasic region is required for interaction with its effector PRK1Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PESTPak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanismMixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathwaysGroup I and II mammalian PAKs have different modes of activation by Cdc42Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasionRac GTPase signaling through the PP5 protein phosphatasePak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expressionActivated Rac1 GTPase translocates protein phosphatase 5 to the cell membrane and stimulates phosphatase activity in vitroErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblastsControl of Dendritic Spine Morphological and Functional Plasticity by Small GTPasesThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesA RAC/CDC-42-independent GIT/PIX/PAK signaling pathway mediates cell migration in C. elegansStretching morphogenesis of the roof plate and formation of the central canalPhosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverCrystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKsUpregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injuryJAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functionsPAK1 is a novel cardiac protective signaling moleculeIdentification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cellsP21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformationA preferred AMPK phosphorylation site adjacent to the inhibitory loop of cardiac and skeletal troponin IDlc1 interaction with non-muscle myosin heavy chain II-A (Myh9) and Rac1 activationDissecting activation of the PAK1 kinase at protrusions in living cells.p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic propertiesThe Toca-1-N-WASP complex links filopodial formation to endocytosisActivation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells.PAK1-Nck regulates cyclin D1 promoter activity in response to prolactinIncreased smooth muscle cell activation and neointima formation in response to injury in AIF-1 transgenic miceFocal adhesion kinase as a regulator of cell tension in the progression of cancer.PAK kinase regulates Rac GTPase and is a potential target in human schwannomasp27(Kip1) controls cytokinesis via the regulation of citron kinase activation.Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion.Coordination of Rho family GTPase activities to orchestrate cytoskeleton responses during cell wound repair.PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.Natural products active in aberrant c-Kit signaling.Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation.Physcomitrella patens: a model to investigate the role of RAC/ROP GTPase signalling in tip growth.
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P2860
PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
PAK and other Rho-associated k ...... verse mechanisms of regulation
@ast
PAK and other Rho-associated k ...... verse mechanisms of regulation
@en
type
label
PAK and other Rho-associated k ...... verse mechanisms of regulation
@ast
PAK and other Rho-associated k ...... verse mechanisms of regulation
@en
prefLabel
PAK and other Rho-associated k ...... verse mechanisms of regulation
@ast
PAK and other Rho-associated k ...... verse mechanisms of regulation
@en
P2860
P356
P1433
P1476
PAK and other Rho-associated k ...... verse mechanisms of regulation
@en
P2093
Zhou-shen Zhao
P2860
P304
P356
10.1042/BJ20041638
P407
P577
2005-03-01T00:00:00Z