Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
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The role of purinergic receptors in cancer-induced bone painNociceptive transmission and modulation via P2X receptors in central pain syndromeBrain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic painIntrinsic properties and regulation of Pannexin 1 channel.The pannexins: past and presentGenome-wide association study of selenium concentrationsInsights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide PolymorphismsP2X ion channel receptors and inflammationConnexins and Pannexins: New Insights into Microglial Functions and DysfunctionsEmerging targets in neuroinflammation-driven chronic painP2X7 Cell Death Receptor Activation and Mitochondrial Impairment in Oxaliplatin-Induced Apoptosis and Neuronal Injury: Cellular Mechanisms and In Vivo ApproachAnimal models of chronic pain: Advances and challenges for clinical translation.Hematopoietic pannexin 1 function is critical for neuropathic painPannexin-1 as a potentiator of ligand-gated receptor signaling.Physiological mechanisms for the modulation of pannexin 1 channel activity.Heritability of nociception IV: neuropathic pain assays are genetically distinct across methods of peripheral nerve injury.Pain vulnerability: a neurobiological perspective.Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120.Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine.A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat.Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice.Neuromodulation by extracellular ATP and P2X receptors in the CNS.Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.Pathological pain and the neuroimmune interface.Towards a mechanism-based approach to pain management in osteoarthritisNon-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkersQuantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse.Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory painHaplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal gangliaReflecting on pain management for patients with osteoarthritis and other rheumatic disorders: there's more to pain management than managing painModeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.P2X7 on Mouse T Cells: One Channel, Many FunctionsThe serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonistsP2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis?Current challenges in translational pain research.P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2.Natural hair color and questionnaire-reported pain among women in the United States.
P2860
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P2860
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@ast
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@en
type
label
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@ast
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@en
prefLabel
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@ast
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@en
P2093
P2860
P356
P1433
P1476
Genetically determined P2X7 re ...... y in chronic pain sensitivity.
@en
P2093
Clifford J Woolf
David Tichauer
Dmitri V Zaykin
Edith Gershon
Gary D Slade
Gary Peltz
Jean-Sebastien Austin
Jeffrey S Mogil
Jessica Livneh
Joanne Jordan
P2860
P2888
P304
P356
10.1038/NM.2710
P407
P577
2012-03-25T00:00:00Z
P5875
P6179
1006175749