Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans
about
Synthetic biology of fungal natural productsThe Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine MicroorganismsLessons learned from the transformation of natural product discovery to a genome-driven endeavorBiochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide BiosynthesisDiversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases.Engineering synthetic recursive pathways to generate non-natural small molecules.Accurate prediction of secondary metabolite gene clusters in filamentous fungi.Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis.Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulansThioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis.Engineering unnatural variants of plantazolicin through codon reprogramming.Diversity-Oriented Combinatorial Biosynthesis of Hybrid Polyketide Scaffolds from Azaphilone and Benzenediol Lactone Biosynthons.Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases.Synthetic biological approaches to natural product biosynthesis.Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics.Strategies for mining fungal natural products.Genetics of Polyketide Metabolism in Aspergillus nidulans.Recent advances in combinatorial biosynthesis for drug discoveryGenetic regulation and manipulation for natural product discovery.Breaking the silence: protein stabilization uncovers silenced biosynthetic gene clusters in the fungus Aspergillus nidulans.Navigating the fungal polyketide chemical space: from genes to molecules.Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products.Genetic localization and in vivo characterization of a Monascus azaphilone pigment biosynthetic gene cluster.FunGeneClusterS: Predicting fungal gene clusters from genome and transcriptome data.Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain
P2860
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P2860
Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
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name
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@ast
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@en
type
label
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@ast
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@en
prefLabel
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@ast
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@en
P2093
P2860
P921
P356
P1476
Engineering of an "unnatural" ...... omains in Aspergillus nidulans
@en
P2093
Amber D Somoza
Clay C C Wang
P2860
P304
13314-13316
P356
10.1021/JA205780G
P407
P577
2011-08-10T00:00:00Z