Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
about
Recent advances in malaria drug discoveryAntibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?Recent progress in the development of anti-malarial quinolones.Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.Targeting the redox metabolism of Plasmodium falciparum.Novel inhibitors of the Plasmodium falciparum electron transport chain.Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties.Transition metal-free one-pot synthesis of 2-substituted 3-carboxy-4-quinolone and chromone derivatives.Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors.2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties
P2860
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P2860
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@ast
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@en
type
label
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@ast
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@en
prefLabel
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@ast
Identification, design and bio ...... inone oxidoreductase (PfNDH2).
@en
P2093
P2860
P50
P356
P1476
Identification, design and bio ...... uinone oxidoreductase (PfNDH2)
@en
P2093
Abhishek Srivastava
Alasdair Hill
Alison E Shone
Alison Mbekeani
Ashley J Warman
Bénédicte Pacorel
Chandrakala Pidathala
Lee Taylor
Nicholas E Fisher
Olivier Berger
P2860
P304
P356
10.1021/JM201184H
P407
P577
2012-02-24T00:00:00Z