Pharmacological inhibitors of glycogen synthase kinase 3.
about
Glycogen synthase kinase 3: more than a namesakeZM336372 induces apoptosis associated with phosphorylation of GSK-3beta in pancreatic adenocarcinoma cell linesActomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growthTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderWnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cellsThe Wnt-dependent signaling pathways as target in oncology drug discoveryHyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer diseaseGlycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and ImagingKinases as druggable targets in trypanosomatid protozoan parasitesReview of pharmacological treatment in mood disorders and future directions for drug development.A framework for the establishment of a cnidarian gene regulatory network for "endomesoderm" specification: the inputs of ß-catenin/TCF signalingCell migration in paediatric glioma; characterisation and potential therapeutic targeting.Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6Wnt signaling networks in autism spectrum disorder and intellectual disabilityAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemNovel reporter alleles of GSK-3α and GSK-3βGSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosisGSK-3beta activity is increased in skeletal muscle after burn injury in ratsInhibition of glycogen synthase kinase 3[beta] activity with lithium in vitro attenuates sepsis-induced changes in muscle protein turnoverRegulation of Alzheimer's disease amyloid-beta formation by casein kinase IChemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signalingGenetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.Glycogen synthase kinase-3 in the etiology and treatment of mood disorders.Is glycogen synthase kinase-3 a central modulator in mood regulation?Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex.GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animalsFunctional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226.Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo.Efficacy of small-molecule glycogen synthase kinase-3 inhibitors in the postnatal rat model of tau hyperphosphorylationLiposomal packaging generates Wnt protein with in vivo biological activityCadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools.Dynamic telomerase gene suppression via network effects of GSK3 inhibitionCharacterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling.A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activityStructure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.Lithium enhances axonal regeneration in peripheral nerve by inhibiting glycogen synthase kinase 3β activation.Exogenous activation of Wnt/β-catenin signaling attenuates binge alcohol-induced deficient bone fracture healing.A new avenue for lithium: intervention in traumatic brain injury.Inhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in miceConstitutive glycogen synthase kinase-3alpha/beta activity protects against chronic beta-adrenergic remodelling of the heart.
P2860
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P2860
Pharmacological inhibitors of glycogen synthase kinase 3.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Pharmacological inhibitors of glycogen synthase kinase 3.
@ast
Pharmacological inhibitors of glycogen synthase kinase 3.
@en
type
label
Pharmacological inhibitors of glycogen synthase kinase 3.
@ast
Pharmacological inhibitors of glycogen synthase kinase 3.
@en
prefLabel
Pharmacological inhibitors of glycogen synthase kinase 3.
@ast
Pharmacological inhibitors of glycogen synthase kinase 3.
@en
P1476
Pharmacological inhibitors of glycogen synthase kinase 3.
@en
P2093
Laurent Meijer
P304
P356
10.1016/J.TIPS.2004.07.006
P577
2004-09-01T00:00:00Z