Efficacy of the clinical agent VT-1161 against fluconazole-sensitive and -resistant Candida albicans in a murine model of vaginal candidiasis
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Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models.Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.A complex game of hide and seek: the search for new antifungalsStructural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis.New facets of antifungal therapy.Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity.Efficacy of the Investigational Antifungal VT-1161 in Treating Naturally Occurring Coccidioidomycosis in Dogs.Drugs in Clinical Development for Fungal Infections.Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds.Antifungal resistance: current trends and future strategies to combat.An Update on Candida tropicalis Based on Basic and Clinical ApproachesNew Horizons in Antifungal Therapy.VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans.Antifungals discovery: an insight into new strategies to combat antifungal resistance.VT-1598 inhibits the in vitro growth of mucosal Candida strains and protects against fluconazole-susceptible and -resistant oral candidiasis in IL-17 signalling-deficient mice.Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.
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P2860
Efficacy of the clinical agent VT-1161 against fluconazole-sensitive and -resistant Candida albicans in a murine model of vaginal candidiasis
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
@zh-hant
2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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name
Efficacy of the clinical agent ...... e model of vaginal candidiasis
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Efficacy of the clinical agent ...... e model of vaginal candidiasis
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type
label
Efficacy of the clinical agent ...... e model of vaginal candidiasis
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Efficacy of the clinical agent ...... e model of vaginal candidiasis
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prefLabel
Efficacy of the clinical agent ...... e model of vaginal candidiasis
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Efficacy of the clinical agent ...... e model of vaginal candidiasis
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P2093
P2860
P356
P1476
Efficacy of the clinical agent ...... e model of vaginal candidiasis
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E P Garvey
R J Schotzinger
W J Hoekstra
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P304
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10.1128/AAC.00185-15
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2015-06-29T00:00:00Z