SOD1 aggregation in ALS mice shows simplistic test tube behavior. - Wikidata - awgldk - TriplyDB

SOD1 aggregation in ALS mice shows simplistic test tube behavior.

SOD1 aggregation in ALS mice shows simplistic test tube behavior.

http://www.wikidata.org/entity/Q35961208

about

A faulty interaction between SOD1 and hCCS in neurodegenerative disease Thermodynamics of protein destabilization in live cells Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation Non-enzymatic molecular damage as a prototypic driver of aging.Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.Epigenetic changes in T-cell and monocyte signatures and production of neurotoxic cytokines in ALS patients.Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not In vitro Aggregation Propensity.Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111.Biophysical Aspects of Alzheimer's Disease: Implications for Pharmaceutical Sciences : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.How Do Gyrating Beads Accelerate Amyloid Fibrillization?The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.

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P2860

SOD1 aggregation in ALS mice shows simplistic test tube behavior.

http://www.wikidata.org/entity/Q35961208

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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SOD1 aggregation in ALS mice shows simplistic test tube behavior.

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PNAS.1503328112

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

SOD1 aggregation in ALS mice shows simplistic test tube behavior.

@en

P2093

Lisa Lang

http://www.w3.org/2001/XMLSchema#string

Mikael Oliveberg

http://www.w3.org/2001/XMLSchema#string

Per Zetterström

http://www.w3.org/2001/XMLSchema#string

Stefan L Marklund

http://www.w3.org/2001/XMLSchema#string

Thomas Brännström

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanism of prion propagation: amyloid growth occurs by monomer addition

Folding catalysis by transient coordination of Zn2+ to the Cu ligands of the ALS-associated enzyme Cu/Zn superoxide dismutase 1

Global structural motions from the strain of a single hydrogen bond

Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone.

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Cutting off functional loops from homodimeric enzyme superoxide dismutase 1 (SOD1) leaves monomeric β-barrels.

Mosaic copy number variation in human neurons

Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis.

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32

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112

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Jens Danielsson

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280587497

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26221023

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amyotrophic lateral sclerosis

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4538623

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