A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.
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Post-translational modifications as key regulators of TNF-induced necroptosisThe seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosisThe linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumorsp62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.Combination of mTOR and EGFR kinase inhibitors blocks mTORC1 and mTORC2 kinase activity and suppresses the progression of colorectal carcinomaThe association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20.A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expressionTGF-β induces miR-182 to sustain NF-κB activation in glioma subsets.The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death.Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs.A20 inhibits the motility of HCC cells induced by TNF-αA20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death.Transcriptome sequencing of neurologic diseases associated genes in HHV-6A infected human astrocyte.Metabolic enzymes: key modulators of functionality in cancer stem-like cells.Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system.A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-κB activation.MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway.MiR-125a regulates chemo-sensitivity to gemcitabine in human pancreatic cancer cells through targeting A20.A20 targets caspase-8 and FADD to protect HTLV-I-infected cells.Galactose protects hepatocytes against TNF-α-induced apoptosis by promoting activation of the NF-κB signaling pathway in acute liver failure.PD-0332991 induces G1 arrest of colorectal carcinoma cells through inhibition of the cyclin-dependent kinase-6 and retinoblastoma protein axis.Combination of systemic chemotherapy with local stem cell delivered S-TRAIL in resected brain tumors.Effects of silencing RIP1 with siRNA on the biological behavior of the LoVo human colon cancer cell lineTargeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.S-adenosylhomocysteine inhibits NF-κB-mediated gene expression in hepatocytes and confers sensitivity to TNF cytotoxicity.Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death.Necroptosis: Mechanisms and Relevance to Disease.A combination of insulin and ubiquitin A20 promotes osteocalcin expression in adipose-derived stem cells.Bladder polypoid cystitis-derived A20 associates with tumorigenesis.DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.The roadmap of TRAIL apoptotic pathway-targeted cancer therapies: What is next?Loss of A20 in BM-MSCs regulates the Th17/Treg balance in Rheumatoid Arthritis.
P2860
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P2860
A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@ast
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@en
type
label
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@ast
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@en
prefLabel
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@ast
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@en
P2093
P2860
P1433
P1476
A20 ubiquitin ligase-mediated ...... ced apoptosis in glioblastoma.
@en
P2093
Anita C Bellail
Chunhai Hao
Jeffrey J Olson
Xiaolu Yang
Zhijian J Chen
P2860
P304
P356
10.1158/2159-8290.CD-11-0172
P577
2012-01-24T00:00:00Z