Targeting the mitogen-activated protein kinase cascade to treat cancer. - Wikidata - awgldk - TriplyDB

Targeting the mitogen-activated protein kinase cascade to treat cancer.

Targeting the mitogen-activated protein kinase cascade to treat cancer.

http://www.wikidata.org/entity/Q35968411

about

PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer The Role of PPARs in Cancer Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanism Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells RanBPM is an inhibitor of ERK signaling Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer.Molecular Targeting of ERKs/RSK2 Signaling Axis in Cancer Prevention The role of obesity in gastrointestinal cancer: evidence and opinion Serrated pathway in colorectal carcinogenesis Toxin-based therapeutic approaches The INT6 cancer gene and MEK signaling pathways converge during zebrafish development Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial.Expanding the genetic code of Escherichia coli with phosphoserine IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases Stops along the RAS pathway in human genetic disease Loss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cells MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy Exosomes from drug-resistant breast cancer cells transmit chemoresistance by a horizontal transfer of microRNAs The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer A new 2α,5α,10β,14β-tetraacetoxy-4(20),11-taxadiene (SIA) derivative overcomes paclitaxel resistance by inhibiting MAPK signaling and increasing paclitaxel accumulation in breast cancer cells Endo180 binds to the C-terminal region of type I collagen Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux Menin determines K-RAS proliferative outputs in endocrine cells Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape Phenotypic and evolutionary implications of modulating the ERK-MAPK cascade using the dentition as a model Integrative computational biology for cancer research BRAF mutation predicts sensitivity to MEK inhibition SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.RSK in tumorigenesis: connections to steroid signaling.Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis ERK activation causes epilepsy by stimulating NMDA receptor activity Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data.pHUSH: a single vector system for conditional gene expression Mutation analysis of BRAF, MEK1 and MEK2 in 15 ovarian cancer cell lines: implications for therapy.Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets

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P2860

Targeting the mitogen-activated protein kinase cascade to treat cancer.

http://www.wikidata.org/entity/Q35968411

description

2004 nî lūn-bûn

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2004年论文

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2004年论文

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Nature Reviews Cancer

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Targeting the mitogen-activated protein kinase cascade to treat cancer.

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Judith S Sebolt-Leopold

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Roman Herrera

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P2860

Rsk1 mediates a MEK-MAP kinase cell survival signal

Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

Mutations of the BRAF gene in human cancer

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

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10.1038/NRC1503

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