Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids. - Wikidata - awgldk - TriplyDB

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

http://www.wikidata.org/entity/Q35973205

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Synthetic glycolipid activators of natural killer T cells as immunotherapeutic agents Turned on by danger: activation of CD1d-restricted invariant natural killer T cells NKT cell networks in the regulation of tumor immunity The regulatory role of invariant NKT cells in tumor immunity Relationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulations How Rheumatoid Arthritis Can Result from Provocation of the Immune System by Microorganisms and Viruses Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT Cells Glycolipids that Elicit IFN-γ-Biased Responses from Natural Killer T Cells Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver Natural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice.Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells.IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury.Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d.Stimulation of natural killer T cells by glycolipids Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant.Heteroaromatic Moieties in the Sphingosine Backbone of α-Galactosylceramides for Noncovalent Interactions with CD1d Lipid and glycolipid antigens of CD1d-restricted natural killer T cells.Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d.The stimulating adventure of KRN 7000.Distinct and overlapping effector functions of expanded human CD4+, CD8α+ and CD4-CD8α- invariant natural killer T cells In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models.Invariant NKT cells: regulation and function during viral infection.Preclinical evaluation of invariant natural killer T cells in the 5T33 multiple myeloma model Presentation of lipid antigens by CD1 glycoproteins.Elevated expression of LAG-3, but not PD-1, is associated with impaired iNKT cytokine production during chronic HIV-1 infection and treatment.Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy.Synthesis and Biological Activities of 5-Thio-α-GalCers.Gene Expression Profiling and Pathway Network Analysis Predicts a Novel Antitumor Function for a Botanical-Derived Drug, PG2 Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production Design, Synthesis, and Immunological Evaluation of Benzyloxyalkyl-Substituted 1,2,3-Triazolyl α-GalCer Analogues.Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells.Dietary sea cucumber cerebroside alleviates orotic acid-induced excess hepatic adipopexis in rats.Connecting the dots: artificial antigen presenting cell-mediated modulation of natural killer T cells.Glycolipids as immunostimulating agents.CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system.Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis.beta-Glycosphingolipids as immune modulators.Modulation of NKT cells and Th1/Th2 imbalance after alpha-GalCer treatment in progressive load-trained rats.Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation

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P2860

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

http://www.wikidata.org/entity/Q35973205

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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type

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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prefLabel

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

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Proceedings of the National Academy of Sciences of the United States of America

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Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids.

@en

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Chi-Huey Wong

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Douglass Wu

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Jing-Rong Huang

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Jung-Tung Hung

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Masakazu Fujio

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Ya-Jen Chang

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Yi-Chien Tsai

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P2860

Sustained expansion of NKT cells and antigen-specific T cells after injection of alpha-galactosyl-ceramide loaded mature dendritic cells in cancer patients.

Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice.

Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion.

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d

Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development.

Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice.

The regulatory role of Valpha14 NKT cells in innate and acquired immune response.

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10299-10304

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10.1073/PNAS.0703824104

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1-O-(alpha-D-galactopyranosyl)-N-(6-phenylhexanoyl)phytosphingosine

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