The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. - Wikidata - awgldk - TriplyDB

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

http://www.wikidata.org/entity/Q35973393

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Reprogramming, Circular Reasoning and Self versus Non-self: One-Stop Shopping with RNA Editing A-to-I editing of coding and non-coding RNAs by ADARs ADAR1, inosine and the immune sensing system: distinguishing self from non-self To edit or not to edit: regulation of ADAR editing specificity and efficiency The Epitranscriptome and Innate Immunity New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases Rapid and dynamic transcriptome regulation by RNA editing and RNA modifications RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself The dynamic epitranscriptome: A to I editing modulates genetic information RNA editing differently affects protein-coding genes in D. melanogaster and H. sapiens DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA.ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins.Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line.ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer.ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis Understanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'.Aicardi-Goutières syndrome and the type I interferonopathies.DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis Genome-wide profiling of the C. elegans dsRNAome.The role of Alu elements in the cis-regulation of RNA processing.A Phenotypic Screen for Functional Mutants of Human Adenosine Deaminase Acting on RNA 1.The emerging role of RNA editing in plasticity.The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection.STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1 Immunoinflammatory diseases of the central nervous system - the tale of two cytokines.Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.Identification of the long, edited dsRNAome of LPS-stimulated immune cells.Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity Unraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomics Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition.RNA degradation in antiviral immunity and autoimmunity Type I interferonopathies--an expanding disease spectrum of immunodysregulation.Type I interferon dysregulation and neurological disease.Gene regulation in the immune system by long noncoding RNAs.Population and allelic variation of A-to-I RNA editing in human transcriptomes.Dynamic hyper-editing underlies temperature adaptation in Drosophila.ADAR RNA editing below the backbone.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

http://www.wikidata.org/entity/Q35973393

description

2014 nî lūn-bûn

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2014年论文

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2014年论文

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

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J.CELREP.2014.10.041

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA

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A D J Scadden

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David Read

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James Brindle

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Julia Dorin

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Liam P Keegan

http://www.w3.org/2001/XMLSchema#string

Niamh M Mannion

http://www.w3.org/2001/XMLSchema#string

Paul J McLaughlin

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Robert Young

http://www.w3.org/2001/XMLSchema#string

Sam M Greenwood

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P2860

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

Structural Insights into RNA Recognition by RIG-I

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

Pattern recognition receptors and inflammation

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1

Editing independent effects of ADARs on the miRNA/siRNA pathways

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

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10.1016/J.CELREP.2014.10.041

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4

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Michael F Jantsch

Mary A O'Connell

Christoffer Nellåker

Cornelia Vesely

Sarah L McGlasson

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2014-11-13T00:00:00Z

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