Synthesis and biological activities of highly potent antagonists of growth hormone-releasing hormone.
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Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers.Overexpression of the growth-hormone-releasing hormone gene in acromegaly-associated pituitary tumors. An event associated with neoplastic progression and aggressive behavior.Human renal cell carcinoma expresses distinct binding sites for growth hormone-releasing hormone.Antagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca2+-dependent pathway.Mechanisms of synergism between antagonists of growth hormone-releasing hormone and antagonists of luteinizing hormone-releasing hormone in shrinking experimental benign prostatic hyperplasia.Antagonistic analogs of growth hormone-releasing hormone increase the efficacy of treatment of triple negative breast cancer in nude mice with doxorubicin; A preclinical studySynthesis and biological evaluation of antagonists of growth hormone-releasing hormone with high and protracted in vivo activities.Antagonistic actions of analogs related to growth hormone-releasing hormone (GHRH) on receptors for GHRH and vasoactive intestinal peptide on rat pituitary and pineal cells in vitroInhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro.Antagonists of growth hormone-releasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinasesGrowth hormone-releasing hormone antagonist MZ-4-71 inhibits in vivo proliferation of Caki-I renal adenocarcinoma.Increased activity of antagonists of growth hormone-releasing hormone substituted at positions 8, 9, and 10.Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function.Growth hormone-releasing hormone antagonist MZ-5-156 inhibits growth of DU-145 human androgen-independent prostate carcinoma in nude mice and suppresses the levels and mRNA expression of insulin-like growth factor II in tumorsInhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormone.Synthesis of new potent agonistic analogs of growth hormone-releasing hormone (GHRH) and evaluation of their endocrine and cardiac activities.Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers.Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancersAnti-tumor effects of peptide analogs targeting neuropeptide hormone receptors on mouse pheochromocytoma cellsGrowth hormone-releasing hormone receptor antagonists inhibit human gastric cancer through downregulation of PAK1-STAT3/NF-κB signalingEndocrine effects of IGF-I on normal and transformed breast epithelial cells: potential relevance to strategies for breast cancer treatment and prevention.Antagonists of growth hormone-releasing hormone inhibit proliferation induced by inflammation in prostatic epithelial cells.Inhibitory effects of GHRH antagonists on human GH-secreting adenoma tissue.Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer.
P2860
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P2860
Synthesis and biological activities of highly potent antagonists of growth hormone-releasing hormone.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Synthesis and biological activ ...... wth hormone-releasing hormone.
@ast
Synthesis and biological activ ...... wth hormone-releasing hormone.
@en
type
label
Synthesis and biological activ ...... wth hormone-releasing hormone.
@ast
Synthesis and biological activ ...... wth hormone-releasing hormone.
@en
prefLabel
Synthesis and biological activ ...... wth hormone-releasing hormone.
@ast
Synthesis and biological activ ...... wth hormone-releasing hormone.
@en
P2093
P2860
P356
P1476
Synthesis and biological activ ...... wth hormone-releasing hormone.
@en
P2093
Horvath JE
P2860
P304
12298-12302
P356
10.1073/PNAS.91.25.12298
P407
P577
1994-12-01T00:00:00Z