A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis
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Adenosine receptor signaling: a key to opening the blood-brain doorBiological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states.Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking.CD73-generated adenosine is critical for immune regulation during Toxoplasma gondii infection.Anti-inflammatory or proinflammatory effect of an adenosine receptor agonist on the Th17 autoimmune response is inflammatory environment-dependentCharacterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel diseaseThe meninges: new therapeutic targets for multiple sclerosis.Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitisCD73 is expressed by inflammatory Th17 cells in experimental autoimmune encephalomyelitis but does not limit differentiation or pathogenesis.Blocking A2B adenosine receptor alleviates pathogenesis of experimental autoimmune encephalomyelitis via inhibition of IL-6 production and Th17 differentiation.Dual roles of the adenosine A2a receptor in autoimmune neuroinflammationA2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrierUpregulation of adenosine kinase in Rasmussen encephalitis.Histological Architecture Underlying Brain-Immune Cell-Cell Interactions and the Cerebral Response to Systemic Inflammation.Neurotransmitter signaling in the pathophysiology of microglia.Moonlighting adenosine deaminase: a target protein for drug development.Adenosine receptors and epilepsy: current evidence and future potential.The role of adenosine and adenosine receptors in the immunopathogenesis of multiple sclerosis.Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor.Pathological overproduction: the bad side of adenosine.The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets.Oxidative stress and changes in adenosine deaminase activity of cattle experimentally infected by Fasciola hepatica.Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats.Antiproliferative effects of selective adenosine receptor agonists and antagonists on human lymphocytes: evidence for receptor-independent mechanisms.Inhibition of endogenous activated protein C attenuates experimental autoimmune encephalomyelitis by inducing myeloid-derived suppressor cells.Investigation of the conformational dynamics of the apo A2A adenosine receptor.Identification of co-expressed gene signatures in mouse B1, marginal zone and B2 B-cell populations.Multiple sclerosis lymphocytes upregulate A2A adenosine receptors that are antiinflammatory when stimulated.Down-regulation of NTPDase2 and ADP-sensitive P2 Purinoceptors Correlate with Severity of Symptoms during Experimental Autoimmune Encephalomyelitis.Preemptive Caffeine Administration Blocks the Increase in Postoperative Pain Caused by Previous Sleep Loss in the Rat: A Potential Role for Preoptic Adenosine A2A Receptors in Sleep-Pain Interactions.In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease.Upregulation of Neuronal Adenosine A1 Receptor in Human Rasmussen Encephalitis.Adenosine A2A Receptor Signaling in the Immunopathogenesis of Experimental Autoimmune Encephalomyelitis.Purinergic Receptors in Neurological Diseases With Motor Symptoms: Targets for Therapy.High level expression of A2ARs is required for the enhancing function, but not for the inhibiting function, of γδ T cells in the autoimmune responses of EAU.Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity
P2860
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P2860
A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@ast
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@en
type
label
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@ast
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@en
prefLabel
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@ast
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@en
P2093
P2860
P356
P1476
A2A adenosine receptor signali ...... l autoimmune encephalomyelitis
@en
P2093
Antje Krenz
Do-Geun Kim
Jeffrey H Mills
Jiang-Fan Chen
Margaret S Bynoe
P2860
P304
P356
10.4049/JIMMUNOL.1200545
P407
P577
2012-04-23T00:00:00Z